The Spectrum of Mild X-Linked Recessive Muscular Dystrophy

Steven P. Ringel, James Edwin Carroll, S. Clifford Schold

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

We present 19 patients from 12 families with mild (Becker) X-linked recessive dystrophy and compare them with previously described cases. Features in common in the majority of patients include onset after the age of 7 years, walking beyond the age of 20 to 30 years, mild hypertrophy of the calves, mild joint contractures, and high arched feet. Psychometric tests, EEGs, and ECGs were usually normal. Muscle biopsy specimens showed a combination of features, some more characteristic of severe (Duchenne) X-linked dystrophy and others more commonly seen in limb girdle dystrophy. Although there was some variation in the severity between different families, within any one kindred, the clinical picture was quite similar.

Original languageEnglish (US)
Pages (from-to)408-416
Number of pages9
JournalArchives of Neurology
Volume34
Issue number7
DOIs
StatePublished - Jan 1 1977
Externally publishedYes

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Muscular Dystrophies
Contracture
Age of Onset
Psychometrics
Hypertrophy
Walking
Electroencephalography
Electrocardiography
Extremities
Joints
Biopsy
Muscles
Talipes Cavus
Onset
Electroencephalogram

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

The Spectrum of Mild X-Linked Recessive Muscular Dystrophy. / Ringel, Steven P.; Carroll, James Edwin; Schold, S. Clifford.

In: Archives of Neurology, Vol. 34, No. 7, 01.01.1977, p. 408-416.

Research output: Contribution to journalArticle

Ringel, Steven P. ; Carroll, James Edwin ; Schold, S. Clifford. / The Spectrum of Mild X-Linked Recessive Muscular Dystrophy. In: Archives of Neurology. 1977 ; Vol. 34, No. 7. pp. 408-416.
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