The Spectrum of Mild X-Linked Recessive Muscular Dystrophy

Steven P. Ringel, James E. Carroll, S. Clifford Schold

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

We present 19 patients from 12 families with mild (Becker) X-linked recessive dystrophy and compare them with previously described cases. Features in common in the majority of patients include onset after the age of 7 years, walking beyond the age of 20 to 30 years, mild hypertrophy of the calves, mild joint contractures, and high arched feet. Psychometric tests, EEGs, and ECGs were usually normal. Muscle biopsy specimens showed a combination of features, some more characteristic of severe (Duchenne) X-linked dystrophy and others more commonly seen in limb girdle dystrophy. Although there was some variation in the severity between different families, within any one kindred, the clinical picture was quite similar.

Original languageEnglish (US)
Pages (from-to)408-416
Number of pages9
JournalArchives of Neurology
Volume34
Issue number7
DOIs
StatePublished - Jul 1977
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'The Spectrum of Mild X-Linked Recessive Muscular Dystrophy'. Together they form a unique fingerprint.

  • Cite this