Abstract
Much of COVID-19 disease can be attributed to the stable structure of the envelope, which facilitates its transmission; the spike protein and its receptor which determine which tissues get infected and are susceptible to viral and immune cytolysis; and evasion of initiation of type 1 and 3 interferons, which gives the virus a replicative head start and ability to spread while simultaneously compromising the antiviral immune response.
Original language | English (US) |
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Pages (from-to) | 324-326 |
Number of pages | 3 |
Journal | Infectious Diseases in Clinical Practice |
Volume | 28 |
Issue number | 6 |
DOIs | |
State | Published - Nov 1 2020 |
Externally published | Yes |
Keywords
- COVID-19
- SARS CoV-2
- type 1 interferon
- type 3 interferon
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases