Thrombotic thrombocytopenic purpura first seen as massive vaginal necrosis

Deborah C. Gallup, Thomas E. Nolan, David Martin, Donald G. Gallup, Donald M. Sherline

Research output: Contribution to journalArticle


Thrombotic thrombocytopenic purpura is a hematologic disorder that affects the microcirculation. A 38-year-old woman was first seen with fever, thrombocytopenia, and vaginal bleeding. Pelvic examination revealed massive vaginal necrosis. Hematology consultation resulted in agreement with the diagnosis of thrombotic thrombocytopenic purpura. This is the first reported case of thrombotic thrombocytopenic purpura first seen as vaginal necrosis of which we are aware.

Original languageEnglish (US)
Pages (from-to)413-415
Number of pages3
JournalAmerican journal of obstetrics and gynecology
Issue number2
StatePublished - Aug 1991
Externally publishedYes


  • cocaine
  • Thrombotic thrombocytopenic purpura
  • vaginal necrosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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