Thrombotic thrombocytopenic purpura in systemic lupus erythematosus and antiphospholipid antibodies: Effective treatment with plasma exchange and immunosuppression

D. C. Hess, Kapil Dev Sethi, E. Awad

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

We describe 2 patients with systemic lupus erythematosus (SLE) with neurological complications and thrombocytopenia, who, upon further investigation, were found to have thrombotic thrombocytopenic purpura. While neither patient responded to treatment with corticosteroids, both responded to plasma exchange and intravenous cyclophosphamide. This highlights the need to carefully consider this diagnosis in patients with SLE presenting with neurological complications and thrombocytopenia.

Original languageEnglish (US)
Pages (from-to)1474-1478
Number of pages5
JournalJournal of Rheumatology
Volume19
Issue number9
StatePublished - Jan 1 1992

Keywords

  • antiphospholipid antibodies
  • systemic lupus erythematosus
  • thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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