Abstract
Serum thyroxine levels peak earlier and are significantly higher in audiogenic seizure-susceptible DBA/2J mice than in seizure-resistant C57BL/6J mice during early postnatal life. The seizure susceptibility of DBA/2J mice is suppressed by administration of an antithyroid drug or by radiothyroidectomy, while the seizure susceptibility of C57BL/6J mice is enchanced by treatment with excess thyroxine.
Original language | English (US) |
---|---|
Pages (from-to) | 598-600 |
Number of pages | 3 |
Journal | Science |
Volume | 205 |
Issue number | 4406 |
DOIs | |
State | Published - 1979 |
Externally published | Yes |
ASJC Scopus subject areas
- General