The jugular infusion of synthetic TRH (100 μg) initiated a biphasic response of thyroxine in bovine. The first peak was observed within 30 min followed by a decline at 2 hr. The values then showed a gradual elevation up to 6 hr at the conclusion of the experiment. These data indicate that in bovine the biphasic response of TRH may be due to either the direct action of TRH or TSH in the first phase with the second phase due presumably to TSH.
|Original language||English (US)|
|Number of pages||3|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Mar 1974|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)