Toxic leukoencephalopathy due to transdermal fentanyl overdose

Lindsey Foy, Desiree Michelle Seeyave, Stuart A. Bradin

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Children with altered mental status who present to the emergency department have a broad differential diagnosis. We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back. She was found to have changes on brain magnetic resonance imaging consistent with a toxic spongiform leukoencephalopathy but had a good neurologic outcome. This case report illustrates the importance of a thorough physical examination in children in coma and a rarely reported magnetic resonance imaging finding that has been seen in opioid intoxication and is usually associated with severe morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)854-856
Number of pages3
JournalPediatric Emergency Care
Volume27
Issue number9
DOIs
StatePublished - Sep 1 2011
Externally publishedYes

Fingerprint

Leukoencephalopathies
Poisons
Fentanyl
Coma
Magnetic Resonance Imaging
Opioid Analgesics
Nervous System
Physical Examination
Hospital Emergency Service
Differential Diagnosis
Morbidity
Mortality
Brain

Keywords

  • fentanyl overdose
  • opioid intoxication
  • toxic leukoencephalopathy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

Cite this

Toxic leukoencephalopathy due to transdermal fentanyl overdose. / Foy, Lindsey; Seeyave, Desiree Michelle; Bradin, Stuart A.

In: Pediatric Emergency Care, Vol. 27, No. 9, 01.09.2011, p. 854-856.

Research output: Contribution to journalArticle

Foy, Lindsey ; Seeyave, Desiree Michelle ; Bradin, Stuart A. / Toxic leukoencephalopathy due to transdermal fentanyl overdose. In: Pediatric Emergency Care. 2011 ; Vol. 27, No. 9. pp. 854-856.
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