TY - JOUR
T1 - Tracking the 'General'
T2 - Tagging skin-derived dendritic cells
AU - Raju, Raghavan
PY - 2004/2
Y1 - 2004/2
N2 - Dendritic cells (DCs) are the sentinels of the immune system; their migration, maturation and mobilization are fundamental to immunity and tolerance. The recent tracking of DCs from the skin to lymph node (LN) and their enumeration using a Cre/loxP system demonstrate the recruitment of a higher than expected number of DCs to the draining LN after cutaneous administration of DNA-coated gold particles. The longevity of the migrated DCs was also longer than previously reported.
AB - Dendritic cells (DCs) are the sentinels of the immune system; their migration, maturation and mobilization are fundamental to immunity and tolerance. The recent tracking of DCs from the skin to lymph node (LN) and their enumeration using a Cre/loxP system demonstrate the recruitment of a higher than expected number of DCs to the draining LN after cutaneous administration of DNA-coated gold particles. The longevity of the migrated DCs was also longer than previously reported.
UR - http://www.scopus.com/inward/record.url?scp=1642482277&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1642482277&partnerID=8YFLogxK
U2 - 10.1016/j.tibtech.2003.11.005
DO - 10.1016/j.tibtech.2003.11.005
M3 - Short survey
C2 - 14757036
AN - SCOPUS:1642482277
SN - 0167-7799
VL - 22
SP - 58
EP - 59
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 2
ER -