Trigeminal trophic syndrome from stroke

An under-recognized central neuropathic itch syndrome

Ashley R. Curtis, Anne L. Oaklander, Annette Johnson, Gil Yosipovitch

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Trigeminal trophic syndrome (TTS) is the historic name for neuropathic self-induced facial ulceration from abnormal sensory symptoms leading to uncontrolled scratching. Anatomic co-localization of sensory loss (numbness) plus neuropathic itch and pain permits painless scratching. If the itch is severe, some patients will scratch to the point of causing self-injury. Patients may be unaware or may conceal the fact that their lesions are self-induced and thus the diagnosis presents a clinical challenge. Many cases remain undiagnosed, leading to unnecessary and ineffective tests, procedures, and prescribing. We document a patient with a central cause of TTS multiple cerebral vascular accidents and summarize the presentation, pathogenesis, and treatment options.

Original languageEnglish (US)
Pages (from-to)125-128
Number of pages4
JournalAmerican Journal of Clinical Dermatology
Volume13
Issue number2
DOIs
StatePublished - Jan 1 2012

Fingerprint

Stroke
Hypesthesia
Neuralgia
Names
Accidents
Blood Vessels
Wounds and Injuries
Therapeutics

Keywords

  • Cerebral-infarction
  • Imaging
  • Neuropathic-pain
  • Pruritus
  • Self-injurious-behavior.
  • Stroke
  • Trigeminal-neuralgia

ASJC Scopus subject areas

  • Dermatology

Cite this

Trigeminal trophic syndrome from stroke : An under-recognized central neuropathic itch syndrome. / Curtis, Ashley R.; Oaklander, Anne L.; Johnson, Annette; Yosipovitch, Gil.

In: American Journal of Clinical Dermatology, Vol. 13, No. 2, 01.01.2012, p. 125-128.

Research output: Contribution to journalArticle

Curtis, Ashley R. ; Oaklander, Anne L. ; Johnson, Annette ; Yosipovitch, Gil. / Trigeminal trophic syndrome from stroke : An under-recognized central neuropathic itch syndrome. In: American Journal of Clinical Dermatology. 2012 ; Vol. 13, No. 2. pp. 125-128.
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