Tumor lysis syndrome in small cell lung cancer

A. M. Kallab, Anand Jillella

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.

Original languageEnglish (US)
Pages (from-to)149-151
Number of pages3
JournalMedical Oncology
Volume18
Issue number2
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Fingerprint

Tumor Lysis Syndrome
Small Cell Lung Carcinoma
Drug Therapy
Neoplasms
Etoposide
Hematologic Neoplasms
Cisplatin
Lymphoma
Cell Death
Ions
Mortality
Incidence
Therapeutics

Keywords

  • Small cell lung cancer
  • Tumor lysis syndrome

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Tumor lysis syndrome in small cell lung cancer. / Kallab, A. M.; Jillella, Anand.

In: Medical Oncology, Vol. 18, No. 2, 01.01.2001, p. 149-151.

Research output: Contribution to journalArticle

Kallab, A. M. ; Jillella, Anand. / Tumor lysis syndrome in small cell lung cancer. In: Medical Oncology. 2001 ; Vol. 18, No. 2. pp. 149-151.
@article{ae2d82c9c6a446768c792d0315dd44ac,
title = "Tumor lysis syndrome in small cell lung cancer",
abstract = "Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.",
keywords = "Small cell lung cancer, Tumor lysis syndrome",
author = "Kallab, {A. M.} and Anand Jillella",
year = "2001",
month = "1",
day = "1",
doi = "10.1385/MO:18:2:149",
language = "English (US)",
volume = "18",
pages = "149--151",
journal = "Medical Oncology",
issn = "1357-0560",
publisher = "Humana Press",
number = "2",

}

TY - JOUR

T1 - Tumor lysis syndrome in small cell lung cancer

AU - Kallab, A. M.

AU - Jillella, Anand

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.

AB - Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.

KW - Small cell lung cancer

KW - Tumor lysis syndrome

UR - http://www.scopus.com/inward/record.url?scp=0034815718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034815718&partnerID=8YFLogxK

U2 - 10.1385/MO:18:2:149

DO - 10.1385/MO:18:2:149

M3 - Article

C2 - 11778761

AN - SCOPUS:0034815718

VL - 18

SP - 149

EP - 151

JO - Medical Oncology

JF - Medical Oncology

SN - 1357-0560

IS - 2

ER -