Tumor lysis syndrome in small cell lung cancer

A. M. Kallab, Anand Jillella

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.

Original languageEnglish (US)
Pages (from-to)149-151
Number of pages3
JournalMedical Oncology
Volume18
Issue number2
DOIs
Publication statusPublished - Jan 1 2001
Externally publishedYes

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Keywords

  • Small cell lung cancer
  • Tumor lysis syndrome

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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