Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

Charles A. Dinarello, Joseph Gerard Cannon, Sheldon M. Wolff, Harry A. Bernheim, Bruce Beutler, Anthony Cerami, Irene S. Figari, Michael A. Palladino, John V. O’Connor

Research output: Contribution to journalArticle

1113 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)1433-1450
Number of pages18
JournalJournal of Experimental Medicine
Volume163
Issue number6
DOIs
StatePublished - Jun 1 1986

Fingerprint

Interleukin-1
Tumor Necrosis Factor-alpha
Fever
Endotoxins
Rabbits
Prostaglandins E
T-Lymphocytes
leukocyte endogenous mediator
Cell Proliferation
Pyrogens
Horseshoe Crabs
Polymyxin B
Injections
Interleukin-1alpha
Inbred C3H Mouse
Thymocytes
Prostaglandin-Endoperoxide Synthases
Mitogens
Human Activities
Gas Chromatography-Mass Spectrometry

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Dinarello, C. A., Cannon, J. G., Wolff, S. M., Bernheim, H. A., Beutler, B., Cerami, A., ... O’Connor, J. V. (1986). Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. Journal of Experimental Medicine, 163(6), 1433-1450. https://doi.org/10.1084/jem.163.6.1433

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. / Dinarello, Charles A.; Cannon, Joseph Gerard; Wolff, Sheldon M.; Bernheim, Harry A.; Beutler, Bruce; Cerami, Anthony; Figari, Irene S.; Palladino, Michael A.; O’Connor, John V.

In: Journal of Experimental Medicine, Vol. 163, No. 6, 01.06.1986, p. 1433-1450.

Research output: Contribution to journalArticle

Dinarello, CA, Cannon, JG, Wolff, SM, Bernheim, HA, Beutler, B, Cerami, A, Figari, IS, Palladino, MA & O’Connor, JV 1986, 'Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1', Journal of Experimental Medicine, vol. 163, no. 6, pp. 1433-1450. https://doi.org/10.1084/jem.163.6.1433
Dinarello, Charles A. ; Cannon, Joseph Gerard ; Wolff, Sheldon M. ; Bernheim, Harry A. ; Beutler, Bruce ; Cerami, Anthony ; Figari, Irene S. ; Palladino, Michael A. ; O’Connor, John V. / Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. In: Journal of Experimental Medicine. 1986 ; Vol. 163, No. 6. pp. 1433-1450.
@article{6974b16c1b7a43ca92f209708ed7c472,
title = "Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1",
author = "Dinarello, {Charles A.} and Cannon, {Joseph Gerard} and Wolff, {Sheldon M.} and Bernheim, {Harry A.} and Bruce Beutler and Anthony Cerami and Figari, {Irene S.} and Palladino, {Michael A.} and O’Connor, {John V.}",
year = "1986",
month = "6",
day = "1",
doi = "10.1084/jem.163.6.1433",
language = "English (US)",
volume = "163",
pages = "1433--1450",
journal = "Journal of Experimental Medicine",
issn = "0022-1007",
publisher = "Rockefeller University Press",
number = "6",

}

TY - JOUR

T1 - Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

AU - Dinarello, Charles A.

AU - Cannon, Joseph Gerard

AU - Wolff, Sheldon M.

AU - Bernheim, Harry A.

AU - Beutler, Bruce

AU - Cerami, Anthony

AU - Figari, Irene S.

AU - Palladino, Michael A.

AU - O’Connor, John V.

PY - 1986/6/1

Y1 - 1986/6/1

UR - http://www.scopus.com/inward/record.url?scp=0022472749&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022472749&partnerID=8YFLogxK

U2 - 10.1084/jem.163.6.1433

DO - 10.1084/jem.163.6.1433

M3 - Article

VL - 163

SP - 1433

EP - 1450

JO - Journal of Experimental Medicine

JF - Journal of Experimental Medicine

SN - 0022-1007

IS - 6

ER -