Users' Guides to the Medical Literature: III. How to Use an Article About a Diagnostic Test A. Are the Results of the Study Valid?

Roman Jaeschke, Gordon Guyatt, David L. Sackett, Eric Bass, Patrick Brill Edwards, George Browman, Deborah Cook, Michael Farkouh, Hertzel Gerstein, Brian Haynes, Robert Hayward, Anne Holbrook, Elizabeth Juniper, Hui Lee, Mitchell Levine, Virginia Moyer, Jim Nishikawa, Andrew Oxman, Ameen Patel, John PhilbrickW. Scott Richardson, Stephane Sauve, David Sackett, Jack Sinclair, K. S. Trout, Peter Tugwell, Sean Tunis, Stephen Walter, Mark Wilson

Research output: Contribution to journalArticle

953 Scopus citations


You are a medical consultant asked by a surgical colleague to see a 78-year-old woman, now 10 days after abdominal surgery, who has become increasingly short of breath over the last 24 hours. She has also been experiencing what she describes as chest discomfort, which is sometimes made worse by taking a deep breath (but sometimes not). Abnormal findings on physical examination are restricted to residual tenderness in the abdomen and scattered crackles at both lung bases. Chest roentgenogram reveals a small right pleural effusion, but this is the first roentgenogram since the operation. Arterial blood gases show a Po2 of 70 mm Hg, with a saturation of 92%. The electrocardiogram shows only nonspecific changes. You suspect that the patient, despite receiving 5000 U of heparin twice a day,.

Original languageEnglish (US)
Pages (from-to)389-391
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Issue number5
Publication statusPublished - Feb 2 1994
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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