Validation of the good outcome following attempted resuscitation score on in-hospital cardiac arrest in southern Sweden

Marcus Andreas Ohlsson, Linn Maria Kennedy, Mark H. Ebell, Tord Juhlin, Olle Melander

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background There is a great need for a simple and clinically useful instrument to help physicians estimate the probability of survival to discharge with a good neurological outcome (cerebral performance category, CPC = 1) in cases of in-hospital cardiac arrest (IHCA). Our aim was to validate the “Good Outcome Following Attempted Resuscitation” (GO-FAR) score in a different country with different demographics than previously investigated. Methods A retrospective observational study including all cases of IHCA who were part of a cardiac arrest registry at Skåne University Hospital in Sweden 2007–2010. Results Two-hundred-eighty-seven patients suffered IHCA during the period. A majority were male and mean age was 70 years. Overall survival to discharge independent of neurological function was 20.2%; 78% of the survivors had CPC = 1 and survival to discharge with CPC = 1 was 15.7%. The area under the receiver operating characteristics curve for the GO-FAR score was 0.85 (CI = 0.78–0.91, p < 0.001), consistent with very good discrimination. Patients in the group with low or very low probability of survival had a likelihood of 2.8% (95% CI 0.0–6.7), whereas the groups with average and above average probabilities had likelihoods of 8.2% (3.7–13) and 46% (34–58), respectively, for good neurological outcome. This compares with likelihoods of 1.6%, 9.2% and 27.8% in the original study. Conclusion The GO-FAR score accurately predicted the probability of survival to discharge with CPC = 1, even when applied to a different population in another country.

Original languageEnglish (US)
Pages (from-to)294-297
Number of pages4
JournalInternational Journal of Cardiology
Volume221
DOIs
StatePublished - Oct 15 2016

Fingerprint

Heart Arrest
Sweden
Resuscitation
Survival
ROC Curve
Observational Studies
Survivors
Registries
Retrospective Studies
Demography
Physicians
Population

Keywords

  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • Cerebral performance category
  • IHCA
  • Survival score

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Validation of the good outcome following attempted resuscitation score on in-hospital cardiac arrest in southern Sweden. / Ohlsson, Marcus Andreas; Kennedy, Linn Maria; Ebell, Mark H.; Juhlin, Tord; Melander, Olle.

In: International Journal of Cardiology, Vol. 221, 15.10.2016, p. 294-297.

Research output: Contribution to journalArticle

Ohlsson, Marcus Andreas ; Kennedy, Linn Maria ; Ebell, Mark H. ; Juhlin, Tord ; Melander, Olle. / Validation of the good outcome following attempted resuscitation score on in-hospital cardiac arrest in southern Sweden. In: International Journal of Cardiology. 2016 ; Vol. 221. pp. 294-297.
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abstract = "Background There is a great need for a simple and clinically useful instrument to help physicians estimate the probability of survival to discharge with a good neurological outcome (cerebral performance category, CPC = 1) in cases of in-hospital cardiac arrest (IHCA). Our aim was to validate the “Good Outcome Following Attempted Resuscitation” (GO-FAR) score in a different country with different demographics than previously investigated. Methods A retrospective observational study including all cases of IHCA who were part of a cardiac arrest registry at Sk{\aa}ne University Hospital in Sweden 2007–2010. Results Two-hundred-eighty-seven patients suffered IHCA during the period. A majority were male and mean age was 70 years. Overall survival to discharge independent of neurological function was 20.2{\%}; 78{\%} of the survivors had CPC = 1 and survival to discharge with CPC = 1 was 15.7{\%}. The area under the receiver operating characteristics curve for the GO-FAR score was 0.85 (CI = 0.78–0.91, p < 0.001), consistent with very good discrimination. Patients in the group with low or very low probability of survival had a likelihood of 2.8{\%} (95{\%} CI 0.0–6.7), whereas the groups with average and above average probabilities had likelihoods of 8.2{\%} (3.7–13) and 46{\%} (34–58), respectively, for good neurological outcome. This compares with likelihoods of 1.6{\%}, 9.2{\%} and 27.8{\%} in the original study. Conclusion The GO-FAR score accurately predicted the probability of survival to discharge with CPC = 1, even when applied to a different population in another country.",
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