What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report

Sun Jun Kim, Yong D Park, Jay Pillai

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration. The initial MRI examination was normal, followed by progressive left hemispheric cortical atrophy and abnormal high signal intensity over the left occipital, parietal, and cingulate gyral areas over an 18-month period. On the basis of the clinical diagnosis and biopsy findings of Rasmussen syndrome, functional hemispherectomy was carried out at 7.5 years of age with alleviation of clinical seizures for the following 44 months. The follow-up MRI demonstrated atrophic changes involving the remaining left hemisphere with increased signal and cortical volume loss, as well as the absence of abnormal signal in the right hemisphere at 10 years of age. Our MRI findings are consistent with the progression of Rasmussen syndrome in the ipsilateral hemisphere even after functional-hemispherectomy without clinical seizures.

Original languageEnglish (US)
Pages (from-to)250-252
Number of pages3
JournalNeuroradiology
Volume45
Issue number4
DOIs
StatePublished - Apr 1 2003

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Encephalitis
Hemispherectomy
Brain
Seizures
Epilepsia Partialis Continua
Hemiplegia
Gyrus Cinguli
Atrophy
Biopsy

Keywords

  • Functional hemispherectomy
  • Magnetic resonance imaging
  • Rasmussen syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report. / Kim, Sun Jun; Park, Yong D; Pillai, Jay.

In: Neuroradiology, Vol. 45, No. 4, 01.04.2003, p. 250-252.

Research output: Contribution to journalArticle

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