Obstetrics and Gynecology

Research Output

2018

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In : Biology of reproduction. 99, 4, p. 735-748 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Tang, H., Babicheva, A., McDermott, K. M., Gu, Y., Ayon, R. J., Song, S., Wang, Z., Gupta, A., Zhou, T., Sun, X., Dash, S., Wang, Z., Balistrieri, A., Zheng, Q., Cordery, A. G., Desai, A. A., Rischard, F., Khalpey, Z., Wang, J., Black, S. M. & 3 others, Garcia, J. G. N., Makino, A. & Yuan, J. X. J., Feb 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 2, p. L256-L275

Research output: Contribution to journalArticle

41 Scopus citations

Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation

for the NICHD Cooperative Reproductive Medicine Network, May 2018, In : Contemporary Clinical Trials. 68, p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of a Streamlined Oncologist-Led BRCA Mutation Testing and Counseling Model for Patients With Ovarian Cancer

Colombo, N., Huang, G., Scambia, G., Chalas, E., Pignata, S., Fiorica, J., Vanle, L., Ghamande, S. A., González-Santiago, S., Bover, I., Suárez, B. G., Green, A., Huot-Marchand, P., Bourhis, Y., Karve, S. & Blakeley, C., May 1 2018, In : Journal of Clinical Oncology. 36, 13, p. 1300-1307 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment

Prusinski Fernung, L. E., Jones, K., Mas, A., Kleven, D., Waller, J. L. & Al-Hendy, A., Oct 2018, In : American Journal of Pathology. 188, 10, p. 2293-2306 14 p.

Research output: Contribution to journalArticle

Extended Hysterectomy for Selected Cases of Placenta Accreta

Hoffman, M. S., Whiteman, V. E., Bush, S. H. & Devoe, L. D., Jun 2018, In : Journal of Gynecologic Surgery. 34, 3, p. 133-137 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Frequent HPV-independent p16/INK4A overexpression in head and neck cancer

Lechner, M., Chakravarthy, A. R., Walter, V., Masterson, L., Feber, A., Jay, A., Weinberger, P. M., McIndoe, R. A., Forde, C. T., Chester, K., Kalavrezos, N., O'Flynn, P., Forster, M., Jones, T. M., Vaz, F. M., Hayes, D. N. & Fenton, T. R., Aug 2018, In : Oral Oncology. 83, p. 32-37 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

for the TEDDY Study Group, Apr 2018, In : PLoS Medicine. 15, 4, e1002548.

Research output: Contribution to journalArticle

34 Scopus citations

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In : Oncotarget. 9, 39, p. 25557-25571 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gestational obstructive sleep apnea: Biomarker screening models and lack of postpartum resolution

Street, L. M., Aschenbrenner, C. A., Houle, T. T., Pinyan, C. W. & Eisenach, J. C., Apr 15 2018, In : Journal of Clinical Sleep Medicine. 14, 4, p. 549-555 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

on behalf of & TEDDY study group, Jan 2018, In : Journal of Autoimmunity. 86, p. 93-103 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure

Mohamed, S. A., Shalaby, S. M., Abdelaziz, M., Brakta, S., Hill, W. D., Ismail, N. & Al-Hendy, A., Jan 1 2018, In : Reproductive Sciences. 25, 1, p. 51-63 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human Papillomavirus Genotypes from Vaginal and Vulvar Intraepithelial Neoplasia in Females 15-26 Years of Age

Garland, S. M., Joura, E. A., Ault, K. A., Bosch, F. X., Brown, D. R., Castellsagué, X., Ferenczy, A., Ferris, D. G., Giuliano, A. R., Hernandez-Avila, M., Huh, W. K., Iversen, O. E., Kjaer, S. K., Kurman, R. J., Luna, J., Monsonego, J., Muñoz, N., Paavonen, J., Pitisuttihum, P., Ronnett, B. M. & 11 others, Steben, M., Stoler, M. H., Wheeler, C. M., Wiley, D. J., Perez, G., Saah, A. J., Luxembourg, A., Li, S., DiNubile, M. J., Wagner, M. & Velicer, C., 2018, In : Obstetrics and gynecology. 132, 2, p. 261-270 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins

Dorayappan, K. D. P., Wanner, R., Wallbillich, J. J., Saini, U., Zingarelli, R., Suarez, A., Cohn, D. & Selvendiran, K., Apr 11 2018, In : Oncogene.

Research output: Contribution to journalArticle

42 Scopus citations

Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells

He, X., Song, S., Ayon, R. J., Balisterieri, A., Black, S. M., Makino, A., Wier, W. G., Zang, W. J. & Yuan, J. X. J., Apr 1 2018, In : American Journal of Physiology - Cell Physiology. 314, 4, p. C504-C517

Research output: Contribution to journalArticle

12 Scopus citations

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

TEDDY study group, May 2018, In : Journal of Autoimmunity. 89, p. 90-100 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

12 Scopus citations

JAK/STAT signaling pathway gene expression is reduced following Nelf knockdown in GnRH neurons

Ko, E. K., Chorich, L. P., Sullivan, M. E., Cameron, R. S. & Layman, L. C., Jul 15 2018, In : Molecular and Cellular Endocrinology. 470, p. 151-159 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction

Kvirkvelia, N., McMenamin, M., Warren, M., Jadeja, R. N., Kodeboyina, S. K., Sharma, A., Zhi, W., O'Connor, P. M., Raju, R., Lucas, R. & Madaio, M. P., Aug 2018, In : Kidney International. 94, 2, p. 280-291 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

KLHL5 knockdown increases cellular sensitivity to anticancer drugs

Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. & She, J. X., Dec 1 2018, In : Oncotarget. 9, 100, p. 37429-37438 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Letter to the Editor: "Higher TSH Levels Within the Normal Range Are Associated With Unexplained Infertility"

Diamond, M. P., Huang, H., Gracia, C., Santoro, N. & Zhang, H., Aug 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 8, p. 3110-3111 2 p.

Research output: Contribution to journalLetter

LPS-induced acute lung injury involves NF-kB–mediated downregulation of SOX18

Gross, C. M., Kellner, M., Wang, T., Lu, Q., Sun, X., Zemskov, E. A., Noonepalle, S., Kangath, A., Kumar, S., Gonzalez-Garay, M., Desai, A. A., Aggarwal, S., Gorshkov, B., Klinger, C., Verin, A. D., Catravas, J. D., Jacobson, J. R., Yuan, J. X. J., Rafikov, R., Garcia, J. G. N. & 1 others, Black, S. M., May 1 2018, In : American journal of respiratory cell and molecular biology. 58, 5, p. 614-624 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Major depression, antidepressant use, and male and female fertility

Reproductive Medicine Network, May 2018, In : Fertility and sterility. 109, 5, p. 879-887 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Management of herpes zoster (shingles) during pregnancy

Hayward, K., Cline, A., Stephens, A. & Street, L. M., Oct 3 2018, In : Journal of Obstetrics and Gynaecology. 38, 7, p. 887-894 8 p.

Research output: Contribution to journalReview article

5 Scopus citations

Management of Obstructive Sleep Apnea in Pregnancy

Dominguez, J. E., Street, L. & Louis, J., Jun 2018, In : Obstetrics and Gynecology Clinics of North America. 45, 2, p. 233-247 15 p.

Research output: Contribution to journalReview article

6 Scopus citations

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature communications. 9, 1, 258.

Research output: Contribution to journalArticle

21 Scopus citations

Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids

Yang, Q. & Al-Hendy, A., May 1 2018, In : Fertility and Sterility. 109, 5, p. 802-803 2 p.

Research output: Contribution to journalEditorial

Novel expression of CD11b in epithelial ovarian cancer: Potential therapeutic target

Saed, G. M., Fletcher, N. M., Diamond, M. P., Morris, R. T., Gomez-Lopez, N. & Memaj, I., Mar 2018, In : Gynecologic Oncology. 148, 3, p. 567-575 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes

Kong, J. N., Zhu, Z., Itokazu, Y., Wang, G., Dinkins, M. B., Zhong, L., Lin, H. P., Elsherbini, A., Leanhart, S., Jiang, X., Qin, H., Zhi, W., Spassieva, S. D. & Bieberich, E., 2018, In : Journal of Lipid Research. 59, 3, p. 488-506 19 p.

Research output: Contribution to journalArticle

15 Scopus citations

Obstructive sleep apnea in pregnancy - What you need to know

Louis, J. & Street, L. M., Feb 1 2018, In : Contemporary Ob/Gyn. 2018, February

Research output: Contribution to journalComment/debate

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Park, M. J., Shen, H., Spaeth, J. M., Tolvanen, J. H., Failor, C., Knudtson, J. F., McLaughlin, J., Halder, S. K., Yang, Q., Bulun, S. E., Al-Hendy, A., Schenken, R. S., Aaltonen, L. A. & Boyer, T. G., Mar 30 2018, In : Journal of Biological Chemistry. 293, 13, p. 4870-4882 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

for the TEDDY Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

PDL-1 blockade prevents T cell exhaustion, inhibits autophagy, and promotes clearance of Leishmania donovani

Habib, S., El Andaloussi, A., Elmasry, K., Handoussa, A., Azab, M., Elsawey, A., Al-Hendy, A. & Ismail, N., Jun 1 2018, In : Infection and Immunity. 86, 6, e00019-18.

Research output: Contribution to journalArticle

11 Scopus citations

Pediatric Foley Catheter Placement After Operative Hysteroscopy Does Not Cause Ascending Infection

Abuzeid, O. M., Hebert, J., Ashraf, M., Mitwally, M., Diamond, M. P. & Abuzeid, M. I., Jan 2018, In : Journal of Minimally Invasive Gynecology. 25, 1, p. 133-138 6 p.

Research output: Contribution to journalArticle

Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Predictive modeling for determination of microscopic residual disease at primary cytoreduction: An NRG Oncology/Gynecologic Oncology Group 182 Study

Horowitz, N. S., Larry Maxwell, G., Miller, A., Hamilton, C. A., Rungruang, B., Rodriguez, N., Richard, S. D., Krivak, T. C., Fowler, J. M., Mutch, D. G., Van Le, L., Lee, R. B., Argenta, P., Bender, D., Tewari, K. S., Gershenson, D., Java, J. J. & Bookman, M. A., Jan 2018, In : Gynecologic Oncology. 148, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 154.

Research output: Contribution to journalArticle

4 Scopus citations

Proteomic alterations in aqueous humor from patients with primary open angle glaucoma

Sharma, S., Bollinger, K. E., Kodeboyina, S. K., Zhi, W., Patton, J., Bai, S., Edwards, B., Ulrich, L., Bogorad, D. & Sharma, A., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2635-2643 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

STAT3/PIAS3 levels serve as "early signature" genes in the development of high-grade serous carcinoma from the fallopian tube

Saini, U., Suarez, AA., Naidu, S., Wallbillich, J. J., Bixel, K., RA, W., Bice, J., Kladney, RD., Lester, J., Karlan, B. Y., Goodfellow, PJ., Cohn, DE. & Selvendiran, K., Jan 16 2018, In : Cancer Research.

Research output: Contribution to journalArticle

7 Scopus citations

Successes and failures of uterine leiomyoma drug discovery

Ali, M., Chaudhry, Z. T. & Al-Hendy, A., Feb 1 2018, In : Expert Opinion on Drug Discovery. 13, 2, p. 169-177 9 p.

Research output: Contribution to journalReview article

12 Scopus citations

Targeted knockout of a chemokine-like gene increases anxiety and fear responses

Choi, J. H., Jeong, Y. M., Kim, S., Lee, B., Ariyasiri, K., Kim, H. T., Jung, S. H., Hwang, K. S., Choi, T. I., Park, C. O., Huh, W. K., Carl, M., Rosenfeld, J. A., Raskin, S., Ma, A., Gecz, J., Kim, H. G., Kim, J. S., Shin, H. C., Park, D. S. & 7 others, Gerlai, R., Jamieson, B. B., Kim, J. S., Iremonger, K. J., Lee, S. H., Shin, H. S. & Kim, C. H., Jan 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. E1041-E1050

Research output: Contribution to journalArticle

9 Scopus citations

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

24 Scopus citations

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In : Nature. 562, 7728, p. 583-588 6 p.

Research output: Contribution to journalArticle

190 Scopus citations

The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design

Stewart, E. A., Lytle, B. L., Thomas, L., Wegienka, G. R., Jacoby, V., Diamond, M. P., Nicholson, W. K., Anchan, R. M., Venable, S., Wallace, K., Marsh, E. E., Maxwell, G. L., Borah, B. J., Catherino, W. H. & Myers, E. R., Jul 2018, In : American journal of obstetrics and gynecology. 219, 1, p. 95.e1-95.e10

Research output: Contribution to journalArticle

13 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

The TEDDY study group, Dec 1 2018, In : Current diabetes reports. 18, 12, 136.

Research output: Contribution to journalReview article

13 Scopus citations

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In : Nature. 562, 7728, p. 589-594 6 p.

Research output: Contribution to journalArticle

123 Scopus citations

The ontogeny of myometrial stem cells in OCT4-GFP transgenic mouse model

Brakta, S., Mas, A. & Al-Hendy, A., Nov 29 2018, In : Stem Cell Research and Therapy. 9, 1, 333.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations