Chunhong Yan

Associate Professor

  • 1873 Citations
  • 20 h-Index
19982019
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Gene Expression Medicine & Life Sciences
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Projects 2010 2016

Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factors
Neoplasms
High-Throughput Screening Assays
Preclinical Drug Evaluations

The Role of ATF3 in the DNA Damage Response

Yan, C.

National Institutes of Health

9/1/106/30/16

Project: Research projectResearch Project

DNA Damage
Neoplasms
Carcinogenesis
Histone Acetyltransferases
Genetically Modified Animals

Research Output 1998 2019

  • 1873 Citations
  • 20 h-Index
  • 54 Article
  • 2 Chapter
  • 2 Review article
  • 1 Short survey

Discovery, synthesis of novel fusidic acid derivatives possessed amino-terminal groups at the 3-hydroxyl position with anticancer activity

Ni, J., Guo, M., Cao, Y., Lei, L., Liu, K., Wang, B., Lu, F., Zhai, R., Gao, X., Yan, C., Wang, H. & Bi, Y., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 122-131 10 p.

Research output: Contribution to journalArticle

Fusidic Acid
Hydroxyl Radical
Tumors
Derivatives
Neoplasms
1 Citations

Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice

Wang, Z., He, Y., Deng, W., Lang, L., Yang, H., Jin, B., Kolhe, R. B., Ding, H., Zhang, J., Hai, T. & Yan, C., Jan 4 2018, In : Oncogene. 37, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
Genomic Instability
Carcinogenesis
Neoplasms
DNA Damage
5 Citations

H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo

Yang, Y., Guan, D., Lei, L., Lu, J., Liu, J. Q., Yang, G., Yan, C., Zhai, R., Tian, J., Bi, Y., Fu, F. & Wang, H., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 98-105 8 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
P-Glycoprotein
Paclitaxel
Derivatives
Rhodamine 123

Rnf126 as a biomarker of a poor prognosis in invasive breast cancer and chek1 inhibitor efficacy in breast cancer cells

Yang, X., Pan, Y., Qiu, Z., Du, Z., Zhang, Y., Fa, P., Gorityala, S., Ma, S., Li, S., Chen, C., Wang, H., Xu, Y., Yan, C., Ruth, K., Ma, Z. & Zhang, J., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1629-1643 15 p.

Research output: Contribution to journalArticle

Biomarkers
Breast Neoplasms
Proteins
Staining and Labeling
Ubiquitin-Protein Ligases
1 Citations

Design, synthesis and biological activities of quinazoline containing sorafenib analogs as antitumor agents

Zhang, J., Wang, N., Xie, X., Yan, C., Fu, F., Yao, J. & Wang, H., Jun 1 2017, In : Wuhan University Journal of Natural Sciences. 22, 3, p. 239-246 8 p.

Research output: Contribution to journalArticle

Quinazolines
Cytotoxicity
Bioactivity
Antineoplastic Agents
Cells