• 1355 Citations
  • 21 h-Index
20072020

Research output per year

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Research Output

  • 1355 Citations
  • 21 h-Index
  • 53 Article
  • 9 Review article
  • 1 Comment/debate
  • 1 Letter
2020

Accumulation of kynurenine elevates oxidative stress and alters microRNA profile in human bone marrow stromal cells

Dalton, S., Smith, K., Singh, K., Kaiser, H., Kolhe, R., Mondal, A. K., Khayrullin, A., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S., Feb 2020, In : Experimental Gerontology. 130, 110800.

Research output: Contribution to journalArticle

4 Scopus citations

Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells

Elmansi, A. M., Hussein, K. A., Herrero, S. M., Periyasamy-Thandavan, S., Aguilar-Pérez, A., Kondrikova, G., Kondrikov, D., Eisa, N. H., Pierce, J. L., Kaiser, H., Ding, K. H., Walker, A. L., Jiang, X., Bollag, W. B., Elsalanty, M., Zhong, Q., Shi, X. M., Su, Y., Johnson, M., Hunter, M. & 7 others, Reitman, C., Volkman, B. F., Hamrick, M. W., Isales, C. M., Fulzele, S., McGee-Lawrence, M. E. & Hill, W. D., Jun 2020, In : Bone Reports. 12, 100270.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Freeze-Dried Extracellular Vesicles From Adipose-Derived Stem Cells Prevent Hypoxia-Induced Muscle Cell Injury

El Baradie, K. B. Y., Nouh, M., O’Brien, F., Liu, Y., Fulzele, S., Eroglu, A. & Hamrick, M. W., Mar 20 2020, In : Frontiers in Cell and Developmental Biology. 8, 181.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway

Kondrikov, D. Y., Elmansi, A., Bragg, R. T., Mobley, T., Barrett, T., Eisa, N., Kondrikova, G., Schoeinlein, P., Aguilar-Perez, A., Shi, X. M., Fulzele, S., Lawrence, M. M. G., Hamrick, M., Isales, C. & Hill, W. D., Feb 2020, In : Experimental Gerontology. 130, 110805.

Research output: Contribution to journalArticle

7 Scopus citations

Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity

Ding, K., McGee-Lawrence, M. E., Kaiser, H., Sharma, A. K., Pierce, J. L., Irsik, D. L., Bollag, W. B., Xu, J., Zhong, Q., Hill, W. D., Shi, X. M., Fulzele, S., Kennedy, E. J., Elsalanty, M. E., Hamrick, M. W. & Isales, C. M., May 2020, In : Experimental Gerontology. 133, 110885.

Research output: Contribution to journalArticle

2 Scopus citations

Shape Loss of Autoclaved, Machine-Bent Cobalt-Chrome and Titanium Spine Surgery Rods

Willson, R., Zhou, H., Fulzele, S., Mitchell, S. M. & Chutkan, N., 2020, (Accepted/In press) In : Global Spine Journal.

Research output: Contribution to journalArticle

Open Access
2019

Advances in Molecular biomarker for early diagnosis of Osteoarthritis

Munjal, A., Bapat, S., Hubbard, D., Hunter, M., Kolhe, R. & Fulzele, S., 2019, In : Biomolecular Concepts. 10, 1, p. 111-119 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice

Pandya, C. D., Lee, B., Toque, H. A., Mendhe, B., Bragg, R. T., Pandya, B., Atawia, R. T., Isales, C., Hamrick, M., Caldwell, R. W. & Fulzele, S., 2019, In : Oxidative medicine and cellular longevity. 2019, 1704650.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

Singleton, Q., Vaibhav, K., Braun, M., Patel, C., Khayrullin, A., Mendhe, B., Lee, B. R., Kolhe, R., Kaiser, H., Awad, M. E., Fariyike, T., Elsayed, R., Elsalanty, M., Isales, C. M., Liu, Y., Hamrick, M. W., Dhandapani, K. M. & Fulzele, S., Jan 17 2019, In : Fuel Cells. 8, 1

Research output: Contribution to journalArticle

Identification and clinical validation of a novel 4 gene-signature with prognostic utility in colorectal cancer

Ahluwalia, P., Mondal, A. K., Bloomer, C., Fulzele, S., Jones, K., Ananth, S., Gahlay, G. K., Heneidi, S., Rojiani, A. M., Kota, V. & Kolhe, R., Aug 1 2019, In : International journal of molecular sciences. 20, 15, 3818.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access
5 Scopus citations

Meta-analysis and evidence base for the efficacy of autologous bone marrow mesenchymal stem cells in knee cartilage repair: Methodological guidelines and quality assessment

Awad, M. E., Hussein, K. A., Helwa, I., Abdelsamid, M. F., Aguilar-Perez, A., Mohsen, I., Hunter, M., Hamrick, M. W., Isales, C. M., Elsalanty, M., Hill, W. D. & Fulzele, S., 2019, In : Stem Cells International. 2019, 3826054.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

MicroRNA-141-3p Negatively Modulates SDF-1 Expression in Age-Dependent Pathophysiology of Human and Murine Bone Marrow Stromal Cells

Periyasamy-Thandavan, S., Burke, J., Mendhe, B., Kondrikova, G., Kolhe, R., Hunter, M., Isales, C. M., Hamrick, M. W., Hill, W. D., Fulzele, S., Beerman, I. & Hare, J., Aug 16 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 9, p. 1368-1374 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells

Fulzele, S. T., Mendhe, B., Khayrullin, A., Johnson, M. H., Kaiser, H., Liu, Y., Isales, C. M. & Hamrick, M. W., Mar 31 2019, In : Aging. 11, 6, p. 1791-1803 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview

Fariyike, B., Singleton, Q., Hunter, M., Hill, W. D., Isales, C. M., Hamrick, M. W. & Fulzele, S., Mar 2019, In : Mechanisms of Ageing and Development. 178, p. 9-15 7 p.

Research output: Contribution to journalReview article

7 Scopus citations

Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology

Gilbert, W., Bragg, R., Elmansi, A. M., McGee Lawrence, M. E., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S. T., Nov 2019, In : Cytokine. 123, 154783.

Research output: Contribution to journalReview article

2 Scopus citations

Stromal cell-derived factor-1 as a potential therapeutic target for osteoarthritis and rheumatoid arthritis

Bragg, R., Gilbert, W., Elmansi, A. M., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S., 2019, In : Therapeutic Advances in Chronic Disease. 10

Research output: Contribution to journalReview article

Open Access

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands

Elmansi, A. M., Awad, M. E., Eisa, N. H., Kondrikov, D., Hussein, K. A., Aguilar-Pérez, A., Herberg, S., Periyasamy-Thandavan, S., Fulzele, S., Hamrick, M. W., McGee-Lawrence, M. E., Isales, C. M., Volkman, B. F. & Hill, W. D., Jun 2019, In : Pharmacology and Therapeutics. 198, p. 90-108 19 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Current insights on use of growth factors as therapy for Intervertebral Disc Degeneration

Kennon, J. C., Awad, M. E., Chutkan, N., Devine, J. & Fulzele, S., Jan 1 2018, In : Biomolecular Concepts. 9, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Delineating pro-angiogenic myeloid cells in cancer therapy

Johnson, B. W., Achyut, B. R., Fulzele, S., Mondal, A. K., Kolhe, R. & Arbab, A. S., Sep 2018, In : International journal of molecular sciences. 19, 9, 2565.

Research output: Contribution to journalReview article

Effect of plasma-derived extracellular vesicles on erythrocyte deformability in polymicrobial sepsis

Subramani, K., Raju, S. P., Chu, X., Warren, M., Pandya, C. D., Hoda, N., Fulzele, S. & Raju, R., Dec 2018, In : International Immunopharmacology. 65, p. 244-247 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Emerging role of extracellular vesicles in musculoskeletal diseases

Murphy, C., Withrow, J., Hunter, M., Liu, Y., Tang, Y. L., Fulzele, S. & Hamrick, M. W., Apr 2018, In : Molecular Aspects of Medicine. 60, p. 123-128 6 p.

Research output: Contribution to journalReview article

22 Scopus citations

Modulation of miRNAS by vitamin C in human bone marrow stromal cells

Kolhe, R., Mondal, A. K., Pundkar, C., Periyasamy-Thandavan, S., Mendhe, B., Hunter, M., Isales, C. M., Hill, W. D., Hamrick, M. W. & Fulzele, S., Feb 8 2018, In : Nutrients. 10, 2, 186.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Adenosine deaminase-2–induced hyperpermeability in human retinal vascular endothelial cells is suppressed by microRNA-146b-3p

Samra, Y. A., Saleh, H. M., Hussein, K. A., Elsherbiny, N. M., Ibrahim, A. S., Elmasry, K., Fulzele, S., El-Shishtawy, M. M., Eissa, L. A., Al-Shabrawey, M. & Liou, G. I., Feb 2017, In : Investigative Ophthalmology and Visual Science. 58, 2, p. 933-943 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis

Alshenibr, W., Tashkandi, M. M., Alsaqer, S. F., Alkheriji, Y., Wise, A., Fulzele, S., Mehra, P., Goldring, M. B., Gerstenfeld, L. C. & Bais, M. V., Aug 2 2017, In : Arthritis Research and Therapy. 19, 1, 179.

Research output: Contribution to journalArticle

10 Scopus citations

Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity

Zhu, H., Lemos, H., Bhatt, B., Islam, B. N., Singh, A., Gurav, A., Huang, L., Browning, D. D., Mellor, A., Fulzele, S. & Singh, N., Sep 2017, In : PloS one. 12, 9, e0183484.

Research output: Contribution to journalArticle

9 Scopus citations
14 Scopus citations

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Kolhe, R. B., Hunter, D. M., Liu, S., Jadeja, R. N., Pundkar, C., Mondal, A. K., Mendhe, B., Drewry, M., Rojiani, M. V., Liu, Y., Isales, C. M., Guldberg, R. E., Hamrick, M. W. & Fulzele, S. T., Dec 1 2017, In : Scientific reports. 7, 1, 2029.

Research output: Contribution to journalArticle

62 Scopus citations

Hyperhomocysteinemia alters retinal endothelial cells barrier function and angiogenic potential via activation of oxidative stress

Mohamed, R., Sharma, I., Ibrahim, A. S., Saleh, H., Elsherbiny, N. M., Fulzele, S., Elmasry, K., Smith, S. B., Al-Shabrawey, M. & Tawfik, A., Dec 1 2017, In : Scientific reports. 7, 1, 09731.

Research output: Contribution to journalArticle

12 Scopus citations

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Refaey, M. E., McGee-Lawrence, M. E., Fulzele, S., Kennedy, E. J., Bollag, W. B., Elsalanty, M., Zhong, Q., Ding, K. H., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
50 Scopus citations
2016

Advances in Adipose-Derived Stem Cells Isolation, Characterization, and Application in Regenerative Tissue Engineering

Wankhade, U. D., Shen, M., Kolhe, R. & Fulzele, S., 2016, In : Stem Cells International. 2016, 3206807.

Research output: Contribution to journalReview article

70 Scopus citations

AMP-activated protein kinase suppresses autoimmune central nervous system disease by regulating M1-type macrophage-Th17 axis

Mangalam, A. K., Rattan, R., Suhail, H., Singh, J., Hoda, M. N., Deshpande, M., Fulzele, S., Denic, A., Shridhar, V., Kumar, A., Viollet, B., Rodriguez, M. & Giri, S., Aug 1 2016, In : Journal of Immunology. 197, 3, p. 747-760 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model

Bhatta, A., Sangani, R., Kolhe, R., Toque, H. A., Cain, M., Wong, A., Howie, N., Shinde, R., Elsalanty, M., Yao, L., Chutkan, N., Hunter, M., Caldwell, R. B., Isales, C., Caldwell, R. W. & Fulzele, S., Feb 15 2016, In : Molecular and Cellular Endocrinology. 422, p. 211-220 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis

Withrow, J., Murphy, C., Liu, Y., Hunter, M., Fulzele, S. & Hamrick, M. W., Dec 1 2016, In : Arthritis Research and Therapy. 18, 1, 286.

Research output: Contribution to journalReview article

77 Scopus citations
35 Scopus citations
2015

Correlation of changes in the mandible and retina/choroid vasculature of a rat model of BRONJ

Borke, J. L., McAllister, B., Harris, T., Neiberg, M., Guevarra-Toth, C., Fulzele, S. T., Stoianovici, C. & Guerra, C., Sep 1 2015, In : Journal of Cranio-Maxillofacial Surgery. 43, 7, p. 1144-1150 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Pathania, R., Ramachandran, S., Elangovan, S., Padia, R., Yang, P., Cinghu, S., Veeranan-Karmegam, R., Arjunan, P., Gnana-Prakasam, J. P., Sadanand, F., Pei, L., Chang, C. S., Choi, J. H., Shi, H., Manicassamy, S., Prasad, P. D., Sharma, S., Ganapathy, V., Jothi, R. & Thangaraju, M., Apr 22 2015, In : Nature communications. 6, 6910.

Research output: Contribution to journalArticle

117 Scopus citations

MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes

Fulzele, S. T., El-Sherbini, A., Ahmad, S., Sangani, R., Matragoon, S., El-Remessy, A., Radhakrishnan, R. & Liou, G. I., 2015, In : BioMed Research International. 2015, 846501.

Research output: Contribution to journalArticle

44 Scopus citations

MicroRNAs-141 and 200a regulate the SVCT2 transporter in bone marrow stromal cells

Sangani, R., Periyasamy-Thandavan, S., Kolhe, R., Bhattacharyya, M. H., Chutkan, N., Hunter, M., Isales, C., Hamrick, M., Hill, W. D. & Fulzele, S., Jul 5 2015, In : Molecular and Cellular Endocrinology. 410, p. 19-26 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis

Sangani, R., Periyasamy-Thandavan, S., Pathania, R., Ahmad, S., Kutiyanawalla, A., Kolhe, R., Bhattacharyya, M. H., Chutkan, N., Hunter, M., Hill, W. D., Hamrick, M., Isales, C. & Fulzele, S., Sep 1 2015, In : Stem Cell Research. 15, 2, p. 312-321 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

Blackburn, A. R., Hamrick, M. W., Chutkan, N., Sangani, R., Waller, J. L., Corpe, R., Prasad, P. D., Isales, C. M., Ganapathy, V. & Fulzele, S., Jan 8 2014, In : BMC Musculoskeletal Disorders. 15, 1, 9.

Research output: Contribution to journalArticle

1 Scopus citations

Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy

Ahmad, S., Elsherbiny, N. M., Bhatia, K., Elsherbini, A. M., Fulzele, S. T. & Liou, G. I., Dec 15 2014, In : Journal of Neuroimmunology. 277, 1-2, p. 96-104 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Knockdown of SVCT2 impairs in-vitro cell attachment, migration and wound healing in bone marrow stromal cells

Sangani, R., Pandya, C. D., Bhattacharyya, M. H., Periyasamy-Thandavan, S., Chutkan, N., Markand, S., Hill, W. D., Hamrick, M., Isales, C. & Fulzele, S., Mar 2014, In : Stem Cell Research. 12, 2, p. 354-363 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013
27 Scopus citations

ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy

Elsherbiny, N. M., Ahmad, S., Naime, M., Elsherbini, A. M., Fulzele, S., Al-Gayyar, M. M., Eissa, L. A., El-Shishtawy, M. M. & Liou, G. I., Jul 30 2013, In : Life sciences. 93, 2-3, p. 78-88 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

A myostatin inhibitor (propeptide-Fc) increases muscle mass and muscle fiber size in aged mice but does not increase bone density or bone strength

Arounleut, P., Bialek, P., Liang, L. F., Upadhyay, S., Fulzele, S., Johnson, M., Elsalanty, M., Isales, C. M. & Hamrick, M. W., Sep 2013, In : Experimental Gerontology. 48, 9, p. 898-904 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells

Bowser, M., Herberg, S., Arounleut, P., Shi, X., Fulzele, S., Hill, W. D., Isales, C. M. & Hamrick, M. W., Feb 2013, In : Experimental Gerontology. 48, 2, p. 290-297 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Potential role of A2A adenosine receptor in traumatic optic neuropathy

Ahmad, S., Fatteh, N., El-Sherbiny, N. M., Naime, M., Ibrahim, A. S., El-Sherbini, A. M., El-Shafey, S. A., Khan, S., Fulzele, S., Gonzales, J. & Liou, G. I., Oct 2 2013, In : Journal of Neuroimmunology. 264, 1-2, p. 54-64 11 p.

Research output: Contribution to journalArticle

25 Scopus citations