• 56 Citations
  • 5 h-Index
20102019
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Personal profile

Research interests

  • Leukemia
  • Hematology malignancy
  • miRNA
  • lncRNA
  • transcription regulation
  • drug resistance
  • targeted therapy
  • precision medicine

Fingerprint Dive into the research topics where Tianxiang Hu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Lymphoma Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Retroelements Medicine & Life Sciences
Genes Medicine & Life Sciences
zygote Agriculture & Biology
Globins Medicine & Life Sciences

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Research Output 2010 2019

  • 56 Citations
  • 5 h-Index
  • 11 Article
  • 1 Review article
1 Citation (Scopus)

Loss of the BCR-FGFR1 GEF domain suppresses RhoA activation and enhances B-lymphomagenesis in mice

Hu, T., Chong, Y., Lu, S., Qin, H., Ren, M., Savage, N. M., Chang, C. S. & Cowell, J. K., Jan 1 2019, In : Cancer Research. 79, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

Guanidine
Nucleotides
Lymphoma
Leukemia
Stem Cells
1 Citation (Scopus)

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Jan 1 2018, (Accepted/In press) In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Stem Cells
Genes
Stem Cell Niche
1 Citation (Scopus)

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome

Hu, T., Wu, Q., Chong, Y., Qin, H., Poole, C. J., Van Riggelen, J., Ren, M. & Cowell, J. K., Nov 1 2018, In : Leukemia. 32, 11, p. 2363-2373 11 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Phosphotransferases
Stem Cells
Granzymes
6 Citations (Scopus)

MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes

Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In : Cancer Research. 78, 13, p. 3522-3531 10 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Stem Cells
Down-Regulation
Cell Survival
6 Citations (Scopus)

The MIR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

Hu, T., Chong, Y., Qin, H., Kitamura, E., Chang, C. S., Silva, J., Ren, M. & Cowell, J. K., Apr 1 2018, In : Oncogene. 37, 14, p. 1926-1938 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Phosphotransferases
Cell Proliferation
B-Cell Leukemia
Porifera