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Xingjun Fan

Associate Professor

  • 644 Citations
  • 15 h-Index
19972018
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Fingerprint Dive into the research topics where Xingjun Fan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Lenses Medicine & Life Sciences
Crystallins Medicine & Life Sciences
Glutathione Medicine & Life Sciences
Fluorescence Chemical Compounds
Cataract Medicine & Life Sciences
Ascorbic Acid Medicine & Life Sciences
Advanced Glycosylation End Products Medicine & Life Sciences
Amino Acids Chemical Compounds

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Projects

Mechanisms and consequences of impaired glutathione homeostasis in the aging Lens

Fan, X.

Project: Research project

Molecular characterization of the glutathione transport system in the lens

Fan, X.

Project: Research project

Research Output 1997 2018

  • 644 Citations
  • 15 h-Index
  • 38 Article
  • 2 Review article
  • 1 Conference contribution
  • 1 Paper
1 Citation (Scopus)

Estrogen enhances tumor growth and angiogenesis indirectly via mediation of bone marrow-derived cells as well as directly through stimulation of tumor and endothelial cells

Zhuo, Y., Li, X., Zheng, Q., Fan, X., Ma, W., Chen, J., Zhao, X., Zhao, P., Liu, X., Tang, F., Cheng, K. & Feng, W., Oct 2018, In : Oncology Reports. 40, 4, p. 2147-2156 10 p.

Research output: Contribution to journal › Article

Bone Marrow Cells
Estrogens
Endothelial Cells
Growth
Neoplasms
4 Citations (Scopus)

Reactive cysteine residues in the oxidative dimerization and Cu2+ induced aggregation of human γD-crystallin: Implications for age-related cataract

Ramkumar, S., Fan, X., Wang, B., Yang, S. & Monnier, V. M., Nov 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 11, p. 3595-3604 10 p.

Research output: Contribution to journal › Article

Crystallins
Dimerization
Cataract
Cysteine
Disulfides
3 Citations (Scopus)

Gclc deficiency in mouse CNS causes mitochondrial damage and neurodegeneration

Feng, W., Rosca, M., Fan, Y., Hu, Y., Feng, P., Lee, H. G., Monnier, V. M. & Fan, X., Apr 1 2017, In : Human Molecular Genetics. 26, 7, p. 1376-1390 15 p., ddx040.

Research output: Contribution to journal › Article

Central Nervous System
Nesting Behavior
Ligases
Breeding
Glutathione
15 Citations (Scopus)

Lens glutathione homeostasis: Discrepancies and gaps in knowledge standing in the way of novel therapeutic approaches

Fan, X., Monnier, V. M. & Whitson, J., Mar 1 2017, In : Experimental eye research. 156, p. 103-111 9 p.

Research output: Contribution to journal › Review article

Lenses
Glutathione
Homeostasis
Cataract
Capsule Opacification
3 Citations (Scopus)

Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins

Whitson, J. A., Wilmarth, P. A., Klimek, J., Monnier, V. M., David, L. & Fan, X., Dec 1 2017, In : Free Radical Biology and Medicine. 113, p. 84-96 13 p.

Research output: Contribution to journal › Article

Epithelial-Mesenchymal Transition
Heat-Shock Proteins
Proteomics
Lenses
Glutathione