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Research Output 1989 2019

2019

Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia

Wang, L., Cao, Y., Gorshkov, B., Zhou, Y., Yang, Q., Xu, J., Ma, Q., Zhang, X., Wang, J., Mao, X., Zeng, X., Su, Y., Verin, A. D., Hong, M., Liu, Z. & Huo, Y., Aug 2019, In : Pharmacological Research. 146, 104292.

Research output: Contribution to journalArticle

Endotoxemia
Acute Lung Injury
Lipopolysaccharides
Endothelial Cells
Lung
2 Citations (Scopus)

Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis

Barman, S. A., Li, X., Haigh, S., Kondrikov, D., Mahboubi, K., Bordan, Z., Stepp, D. W., Zhou, J., Wang, Y., Weintraub, D. S., Traber, P., Snider, W., Jonigk, D., Sullivan, J., Ryan Crislip, G., Butcher, J. T., Thompson, J., Su, Y., Chen, F. & Fulton, D. J. R., May 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 5, p. L784-L797

Research output: Contribution to journalArticle

Galectin 3
Vascular Smooth Muscle
Pulmonary Hypertension
Smooth Muscle Myocytes
Fibrosis

PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

Cao, Y., Zhang, X., Wang, L., Yang, Q., Ma, Q., Xu, J., Wang, J., Kovacs, L., Ayon, R. J., Liu, Z., Zhang, M., Zhou, Y., Zeng, X., Xu, Y., Wang, Y., Fulton, D. J., Weintraub, N. L., Lucas, R., Dong, Z., Yuan, J. X. J. & 8 others, Sullivan, J. C., Meadows, L., Barman, S. A., Wu, C., Quan, J., Hong, M., Su, Y. & Huo, Y., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13394-13403 10 p.

Research output: Contribution to journalArticle

Open Access
Glycolysis
Pulmonary Hypertension
Lung
Endothelial Cells
Rodentia
Physiological Stress
Cell Survival
Kidney
Wounds and Injuries
Reperfusion
2018
7 Citations (Scopus)

Galectin-3 promotes vascular remodeling and contributes to pulmonary hypertension

Barman, S. A., Chen, F., Li, X., Haigh, S., Stepp, D. W., Kondrikov, D., Mahboubi, K., Bordan, Z., Traber, P., Su, Y. & Fulton, D. J. R., Jun 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1488-1492 5 p.

Research output: Contribution to journalLetter

Galectin 3
Pulmonary Hypertension
Vascular Remodeling
18 Citations (Scopus)

Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

Liu, J., Livingston, M. J., Dong, G., Tang, C., Su, Y., Wu, G., Yin, X. M. & Dong, Z., Mar 1 2018, In : Cell Death and Disease. 9, 3, 322.

Research output: Contribution to journalArticle

trichostatin A
Histone Deacetylase Inhibitors
Autophagy
Acute Kidney Injury
Cisplatin
7 Citations (Scopus)

Hsp70 suppresses mitochondrial reactive oxygen species and preserves pulmonary microvascular barrier integrity following exposure to bacterial toxins

Li, X., Yu, Y., Gorshkov, B., Haigh, S., Bordan, Z., Weintraub, D., Rudic, R. D., Chakraborty, T., Barman, S. A., Verin, A. D., Su, Y., Lucas, R., Stepp, D. W., Chen, F. & Fulton, D. J., Jun 12 2018, In : Frontiers in immunology. 9, JUN, 1309.

Research output: Contribution to journalArticle

Bacterial Toxins
geranylgeranylacetone
Reactive Oxygen Species
Lung
Pneumonia
1 Citation (Scopus)

Inhibition of angiotensin II and calpain attenuates pleural fibrosis

Song, L. J., Xiang, F., Ye, H., Huang, H., Yang, J., Yu, F., Xiong, L., Xu, J. J., Greer, P. A., Shi, H. Z., Xin, J. B., Su, Y. & Ma, W. L., Feb 2018, In : Pulmonary Pharmacology and Therapeutics. 48, p. 46-52 7 p.

Research output: Contribution to journalArticle

Calpain
Angiotensin II
Fibrosis
Bleomycin
Losartan
4 Citations (Scopus)

Polygonum aviculare L. extract and quercetin attenuate contraction in airway smooth muscle

Luo, X., Xue, L., Xu, H., Zhao, Q. Y., Wang, Q., She, Y. S., Zang, D. A., Shen, J., Peng, Y. B., Zhao, P., Yu, M. F., Chen, W., Ma, L. Q., Chen, S., Chen, S., Fu, X., Hu, S., Nie, X., Shen, C., Zou, C. & 7 others, Qin, G., Dai, J., Ji, G., Su, Y., Hu, S., Chen, J. & Liu, Q. H., Dec 1 2018, In : Scientific Reports. 8, 1, 3114.

Research output: Contribution to journalArticle

Polygonum
Quercetin
Smooth Muscle
Acetylcholine
Bronchodilator Agents
2017
5 Citations (Scopus)
Bone Morphogenetic Protein 4
Calpain
Pulmonary Artery
Smooth Muscle Myocytes
Collagen
10 Citations (Scopus)

Calpain-activated mTORC2/Akt pathway mediates airway smooth muscle remodelling in asthma

Rao, S. S., Mu, Q., Zeng, Y., Cai, P. C., Liu, F., Yang, J., Xia, Y., Zhang, Q., Song, L. J., Zhou, L. L., Li, F. Z., Lin, Y. X., Fang, J., Greer, P. A., Shi, H. Z., Ma, W. L., Su, Y. & Ye, H., Feb 1 2017, In : Clinical and Experimental Allergy. 47, 2, p. 176-189 14 p.

Research output: Contribution to journalArticle

Calpain
Smooth Muscle
Asthma
Smooth Muscle Myocytes
Airway Remodeling
7 Citations (Scopus)
Urethral Obstruction
Proximal Kidney Tubule
Fibrosis
Apoptosis
Kidney
11 Citations (Scopus)

Epithelial sodium channel-α mediates the protective effect of the TNF-derived TIP peptide in pneumolysin-induced endothelial barrier dysfunction

Czikora, I., Alli, A. A., Sridhar, S., Matthay, M. A., Pillich, H., Hudel, M., Berisha, B., Gorshkov, B. A., Romero Lucas, M. J., Gonzales, J. N., Wu, G., Huo, Y., Su, Y., Verin, A. D., Fulton, D. J., Chakraborty, T., Eaton, D. C. & Lucas, R., Jul 21 2017, In : Frontiers in immunology. 8, JUL, 842.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Endothelial Cells
Acid Sensing Ion Channels
Lung
Peptides
22 Citations (Scopus)

Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6

Hao, J., Wei, Q., Mei, S., Li, L., Su, Y., Mei, C. & Dong, Z., Jan 1 2017, In : Kidney International. 91, 1, p. 106-118 13 p.

Research output: Contribution to journalArticle

Death Domain Receptors
Reperfusion Injury
MicroRNAs
Kidney
Acute Kidney Injury
22 Citations (Scopus)

miR-18a-5p Inhibits Sub-pleural Pulmonary Fibrosis by Targeting TGF-β Receptor II

Zhang, Q., Ye, H., Xiang, F., Song, L. J., Zhou, L. L., Cai, P. C., Zhang, J. C., Yu, F., Shi, H. Z., Su, Y., Xin, J. B. & Ma, W. L., Mar 1 2017, In : Molecular Therapy. 25, 3, p. 728-738 11 p.

Research output: Contribution to journalArticle

Pulmonary Fibrosis
Bleomycin
Idiopathic Pulmonary Fibrosis
Epithelial-Mesenchymal Transition
Growth Factor Receptors
2 Citations (Scopus)

Redox-dependent calpain signaling in airway and pulmonary vascular remodeling in COPD

Kovacs, L. & Su, Y., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 967. p. 139-160 22 p. (Advances in Experimental Medicine and Biology; vol. 967).

Research output: Chapter in Book/Report/Conference proceedingChapter

Calpain
Chronic Obstructive Pulmonary Disease
Oxidation-Reduction
Lung
Reactive Nitrogen Species
16 Citations (Scopus)

Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophages

Wang, Y., Zhu, J., Zhang, L., Zhang, Z., He, L., Mou, Y., Deng, Y., Cao, Y., Yang, P., Su, Y., Zhao, J., Zhang, S., Yu, Q., Hu, J., Chen, Z., Ning, Q., Xiang, X., Xu, Y., Wang, C. Y. & Xiong, W., Dec 2017, In : Journal of Allergy and Clinical Immunology. 140, 6, p. 1550-1561.e8

Research output: Contribution to journalArticle

STAT6 Transcription Factor
Transcription Factor CHOP
Interleukin-4 Receptors
Endoplasmic Reticulum Stress
Interleukin-4
12 Citations (Scopus)

The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

Li, C., Wei, Z., Fan, Y., Huang, W., Su, Y., Li, H., Dong, Z., Fukuda, M., Khater, M. & Wu, G., Oct 24 2017, In : Cell Reports. 21, 4, p. 1089-1101 13 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
G-Protein-Coupled Receptors
Sorting
Endoplasmic Reticulum
Membrane Proteins
2016
14 Citations (Scopus)

Activation of calpain-2 by mediators in pulmonary vascular remodeling of pulmonary arterial hypertension

Kovacs, L., Han, W., Rafikov, R., Bagi, Z., Offermanns, S., Saido, T. C., Black, S. M. & Su, Y., Mar 2016, In : American journal of respiratory cell and molecular biology. 54, 3, p. 384-393 10 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Hypertension
Chemical activation
Lung
Muscle
10 Citations (Scopus)

Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosis

Yang, J., Xiang, F., Cai, P. C., Lu, Y. Z., Xu, X. X., Yu, F., Li, F. Z., Greer, P. A., Shi, H. Z., Zhou, Q., Xin, J. B., Ye, H., Su, Y. & Ma, W. L., Jul 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 1, p. L145-L153

Research output: Contribution to journalArticle

Calpain
Renin-Angiotensin System
Fibrosis
Pleural Effusion
Pleural Tuberculosis
10 Citations (Scopus)

Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cells

Abeyrathna, P., Kovacs, L., Han, W. & Su, Y., Jul 1 2016, In : American Journal of Physiology - Cell Physiology. 311, 1, p. C24-C34

Research output: Contribution to journalArticle

Calpain
Transforming Growth Factors
Platelet-Derived Growth Factor
Pulmonary Artery
Smooth Muscle Myocytes
32 Citations (Scopus)

Chop deficiency protects mice against bleomycin-induced pulmonary fibrosis by attenuating M2 macrophage production

Yao, Y., Wang, Y., Zhang, Z., He, L., Zhu, J., Zhang, M., He, X., Cheng, Z., Ao, Q., Cao, Y., Yang, P., Su, Y., Zhao, J., Zhang, S., Yu, Q., Ning, Q., Xiang, X., Xiong, W., Wang, C. Y. & Xu, Y., May 1 2016, In : Molecular Therapy. 24, 5, p. 915-925 11 p.

Research output: Contribution to journalArticle

Transcription Factor CHOP
Protein Deficiency
Pulmonary Fibrosis
Bleomycin
Macrophages
10 Citations (Scopus)

Preexisting smooth muscle cells contribute to neointimal cell repopulation at an incidence varying widely among individual lesions

Yang, P., Hong, M. S., Fu, C., Schmit, B. M., Su, Y., Berceli, S. A. & Jiang, Z., Feb 1 2016, In : Surgery (United States). 159, 2, p. 602-612 11 p.

Research output: Contribution to journalArticle

Common Carotid Artery
Smooth Muscle Myocytes
Femoral Artery
Endothelial Cells
Incidence
2015
25 Citations (Scopus)

Bleomycin induced epithelial-mesenchymal transition (EMT) in pleural mesothelial cells

Chen, L. J., Ye, H., Zhang, Q., Li, F. Z., Song, L. J., Yang, J., Mu, Q., Rao, S. S., Cai, P. C., Xiang, F., Zhang, J. C., Su, Y., Xin, J. B. & Ma, W. L., Mar 1 2015, In : Toxicology and Applied Pharmacology. 283, 2, p. 75-82 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Bleomycin
Idiopathic Pulmonary Fibrosis
Fibrosis
Collagen
4 Citations (Scopus)

CAT-1 as a novel CAM stabilizes endothelial integrity and mediates the protective actions of l-Arg via a NO-independent mechanism

Guo, L., Tian, S., Chen, Y., Mao, Y., Cui, S., Hu, A., Zhang, J., Xia, S. L., Su, Y., Du, J., Block, E. R., Wang, X. L. & Cui, Z., Oct 1 2015, In : Journal of molecular and cellular cardiology. 87, p. 180-191 12 p.

Research output: Contribution to journalArticle

Cationic Amino Acid Transporter 1
Cell Adhesion Molecules
Intercellular Junctions
Basic Amino Acid Transport Systems
Catenins
26 Citations (Scopus)

Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis

Li, F. Z., Cai, P. C., Song, L. J., Zhou, L. L., Zhang, Q., Rao, S. S., Xia, Y., Xiang, F., Xin, J. B., Greer, P. A., Shi, H. Z., Su, Y., Ma, W. L. & Ye, H., Sep 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 9, p. 1796-1804 9 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Fibrosis
Collagen
Lung
Fibroblasts
33 Citations (Scopus)

EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling

Lu, A., Zuo, C., He, Y., Chen, G., Piao, L., Zhang, J., Xiao, B., Shen, Y., Tang, J., Kong, D., Alberti, S., Chen, D., Zuo, S., Zhang, Q., Yan, S., Fei, X., Yuan, F., Zhou, B., Duan, S., Yu, Y. & 5 others, Lazarus, M., Su, Y., Breyer, R. M., Funk, C. D. & Yu, Y., Mar 2 2015, In : Journal of Clinical Investigation. 125, 3, p. 1228-1242 15 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Prostaglandins
Smooth Muscle Myocytes
Pulmonary Artery
Lung

Erratum:Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species(Free Radical Biology and Medicine (2014) 73 (201-213) (DOI 10.1016/j.freeradbiomed.2014.11.001))

Chen, F., Barman, S. A., Yu, Y., Haigh, S., Wang, Y., Black, S. M., Rafikov, R., Dou, H., Bagi, Z., Han, W., Su, Y. & Fulton, D. J., Jan 1 2015, In : Free Radical Biology and Medicine. 81, 1 p.

Research output: Contribution to journalComment/debate

7 Citations (Scopus)
Apoptosis Inducing Factor
hyperoxia
Hyperoxia
HSP70 Heat-Shock Proteins
caspases
57 Citations (Scopus)
Acute Kidney Injury
Hyperglycemia
Apoptosis
Kidney
Glucose
48 Citations (Scopus)

Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways

Wang, S., Livingston, M. J., Su, Y. & Dong, Z., Jan 1 2015, In : Autophagy. 11, 4, p. 607-616 10 p.

Research output: Contribution to journalArticle

Cilia
Autophagy
Proteasome Endopeptidase Complex
Kidney
Proteasome Inhibitors
16 Citations (Scopus)

SUMOylation occurs in acute kidney injury and plays a cytoprotective role

Guo, C., Wei, Q., Su, Y. & Dong, Z., Mar 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 3, p. 482-489 8 p.

Research output: Contribution to journalArticle

Sumoylation
Acute Kidney Injury
Ubiquitin
Cisplatin
Kidney
76 Citations (Scopus)

The critical role of Akt in cardiovascular function

Abeyrathna, P. & Su, Y., Nov 2015, In : Vascular Pharmacology. 74, p. 38-48 11 p.

Research output: Contribution to journalReview article

Cell Survival
Phosphorylation
Threonine
Vasodilation
Serine
6 Citations (Scopus)

Toll-like receptor 4 signaling inhibits malignant pleural effusion by altering Th1/Th17 responses

Xu, Q. Q., Zhou, Q., Xu, L. L., Lin, H., Wang, X. J., Ma, W. L., Zhai, K., Tong, Z. H., Su, Y. & Shi, H. Z., Oct 1 2015, In : Cell Biology International. 39, 10, p. 1120-1130 11 p.

Research output: Contribution to journalArticle

Malignant Pleural Effusion
Toll-Like Receptor 4
Th17 Cells
Th1 Cells
Cell Differentiation
2014
1 Citation (Scopus)

Airway smooth muscle malfunction in COPD

Su, Y., Nov 1 2014, Calcium Signaling In Airway Smooth Muscle Cells. Springer International Publishing, Vol. 9783319013121. p. 441-457 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pulmonary diseases
Chronic Obstructive Pulmonary Disease
Smooth Muscle
Muscle
Intercellular Signaling Peptides and Proteins
39 Citations (Scopus)

Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species

Chen, F., Barman, S. A., Yu, Y., Haigh, S., Wang, Y., Dou, H., Bagi, Z., Han, W., Su, Y. & Fulton, D. J., Jan 1 2014, In : Free Radical Biology and Medicine. 73, p. 201-213 13 p.

Research output: Contribution to journalArticle

Caveolin 1
NADPH Oxidase
Reactive Oxygen Species
Pulmonary Artery
Pulmonary Hypertension
6 Citations (Scopus)

Cotinine concentration in serum correlates with tobacco smoke-induced emphysema in mice

Xu, X., Su, Y. & Fan, Z. H., Jan 27 2014, In : Scientific Reports. 4, 3864.

Research output: Contribution to journalArticle

Cotinine
Emphysema
Smoke
Tobacco
Serum
6 Citations (Scopus)

Dissociation of FK506-binding protein 12.6 kD from ryanodine receptor in bronchial smooth muscle cells in airway hyperresponsiveness in asthma

Du, Y., Zhao, J., Li, X., Jin, S., Ma, W. L., Mu, Q., Xu, S., Yang, J., Rao, S., Zhu, L., Xin, J., Cai, P. C., Su, Y. & Ye, H., Feb 1 2014, In : American journal of respiratory cell and molecular biology. 50, 2, p. 398-408 11 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Ryanodine Receptor Calcium Release Channel
Smooth Muscle Myocytes
Muscle
Asthma
82 Citations (Scopus)

Endothelial PFKFB3 plays a critical role in angiogenesis

Xu, Y., An, X., Guo, X., Habtetsion, T. G., Wang, Y., Xu, X., Kandala, S., Li, Q., Li, H., Zhang, C., Caldwell, R. B., Fulton, D. J., Su, Y., Hoda, MD. N., Zhou, G., Wu, C. & Huo, Y., Jun 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 6, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Protein Isoforms
Glycolysis
Endothelial Cells
Lactic Acid
30 Citations (Scopus)

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase

Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R. & Black, S. M., Jun 2014, In : American journal of respiratory cell and molecular biology. 50, 6, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Endothelial cells
Endothelin-1
Pulmonary Hypertension
Endothelial Cells
16 Citations (Scopus)

Increasing muscle mass improves vascular function in obese (DB/DB) Mice

Qiu, S., Mintz, J. D., Salet, C. D., Han, W., Giannis, A., Chen, F., Yu, Y., Su, Y., Fulton, D. J. & Stepp, D. W., Jan 1 2014, In : Journal of the American Heart Association. 3, 3, 000854.

Research output: Contribution to journalArticle

Myostatin
Obese Mice
Blood Vessels
Vasodilation
Muscles
65 Citations (Scopus)

NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling

Barman, S. A., Chen, F., Su, Y., Dimitropoulou, C., Wang, Y., Catravas, J. D., Han, W., Orfi, L., Szantai-Kis, C., Keri, G., Szabadkai, I., Barabutis, N., Rafikova, O., Rafikov, R., Black, S. M., Jonigk, D., Giannis, A., Asmis, R., Stepp, D. W., Ramesh, G. & 1 others, Fulton, D. J., Aug 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 8, p. 1704-1715 12 p.

Research output: Contribution to journalArticle

Adventitia
NADPH Oxidase
Pulmonary Artery
Pulmonary Hypertension
Fibroblasts
7 Citations (Scopus)

Novel peptide for attenuation of hyperoxia-induced disruption of lung endothelial barrier and pulmonary edema via modulating peroxynitrite formation

Kondrikov, D., Gross, C., Black, S. M. & Su, Y., Nov 28 2014, In : Journal of Biological Chemistry. 289, 48, p. 33355-33363 9 p.

Research output: Contribution to journalArticle

Hyperoxia
Peroxynitrous Acid
Pulmonary Edema
Apoptosis
Actins
16 Citations (Scopus)

Regulation of endothelial nitric oxide synthase activity by protein-protein interaction

Su, Y., Jan 1 2014, In : Current Pharmaceutical Design. 20, 22, p. 3514-3520 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Proteins
Nitric Oxide Synthase
Dynamin II
Cationic Amino Acid Transporter 1
2013
19 Citations (Scopus)

Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function

Toque, H. A., Nunes, K. P., Yao, L., Xu, Z., Kondrikov, D., Su, Y., Webb, R. C., Caldwell, R. B. & Caldwell, R. W., Jan 1 2013, In : PloS one. 8, 8, p. e72277

Research output: Contribution to journalArticle

Arginase
arginase
blood vessels
Blood Vessels
Medical problems
10 Citations (Scopus)

SUMO1 regulates endothelial function by modulating the overall signals in favor of angiogenesis and homeostatic responses

Yang, P., Zhang, Y., Xu, J., Zhang, S., Yu, Q., Pang, J., Rao, X., Kuczma, M., Marrero, M. B., Fulton, D. J., Kraj, P., Su, Y. & Wang, C. Y., Jan 1 2013, In : American Journal of Translational Research. 5, 4, p. 427-440 14 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
Endothelial cells
Swine
Endothelial Cells
22 Citations (Scopus)

The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis

Ni, J., Dong, Z., Han, W., Kondrikov, D. Y. & Su, Y., Apr 25 2013, In : Free Radical Biology and Medicine. 61, p. 26-39 14 p.

Research output: Contribution to journalArticle

Myofibroblasts
Hyperoxia
Cytoskeleton
Actin Cytoskeleton
Actins
2012
228 Citations (Scopus)

Autophagy in proximal tubules protects against acute kidney injury

Jiang, M., Wei, Q., Dong, G., Komatsu, M., Su, Y. & Dong, Z., Dec 2 2012, In : Kidney International. 82, 12, p. 1271-1283 13 p.

Research output: Contribution to journalArticle

Autophagy
Acute Kidney Injury
Cisplatin
Knockout Mice
Kidney
17 Citations (Scopus)

Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts

Fenouille, N., Grosso, S., Su, Y., Didier, M., Pontier-Bres, R., Imbert, V., Czerucka, D., Caroli-Bosc, F. X., Peyron, J. F. & Lagadec, P., May 1 2012, In : Journal of Pathology. 227, 1, p. 118-129 12 p.

Research output: Contribution to journalArticle

irinotecan
Calpain
Heterografts
Colorectal Neoplasms
Annexin A2
2011
67 Citations (Scopus)

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

Ma, W., Han, W., Greer, P. A., Tuder, R. M., Toque, H. A., Wang, K. K. W., Caldwell, R. W. & Su, Y., Nov 1 2011, In : Journal of Clinical Investigation. 121, 11, p. 4548-4566 19 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Hypertension
Rodentia
Lung
Epidermal Growth Factor