Paul M O'Connor

Associate Professor

  • 1342 Citations
  • 21 h-Index
20042019
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Projects 2014 2019

Renal Hypertension
Inbred Dahl Rats
Salts
Hypertension
Kidney

Research Output 2004 2019

A basic solution to activate the cholinergic anti-inflammatory pathway via the mesothelium?

Mannon, E. C., Sun, J., Wilson, K., Brands, M. W., Martinez-Quinones, P., Baban, B. & O'Connor, P. M., Mar 1 2019, In : Pharmacological Research. 141, p. 236-248 13 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Anti-Inflammatory Agents
Epithelium
Spleen
Vagus Nerve Stimulation

Voltage gated proton channels modulate mitochondrial reactive oxygen species production by complex I in renal medullary thick ascending limb

Patel, B., Zheleznova, N. N., Ray, S. C., Sun, J., Cowley, A. W. & O'Connor, P. M., Jan 1 2019, In : Redox Biology. 101191.

Research output: Contribution to journalArticle

Open Access
Protons
Reactive Oxygen Species
Extremities
Kidney
Electric potential

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J-X., Belin de Chantemele, E. J. & Csanyi, G., Sep 1 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

Imipramine
United States Food and Drug Administration
Pharmaceutical Preparations
Endocytosis
Electron Scanning Microscopy
1 Citation (Scopus)

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction

Kvirkvelia, N., McMenamin, M., Warren, M., Jadeja, R. N., Kodeboyina, S. K., Sharma, A. K., Zhi, W., O'Connor, P. M., Raju, R. P., Lucas, R. & Madaio, M. P., Aug 1 2018, In : Kidney International. 94, 2, p. 280-291 12 p.

Research output: Contribution to journalArticle

Nephritis
Protein Kinase C
Kidney
Protein C Inhibitor
Mitochondrial Proteins
3 Citations (Scopus)

Oral NaHCO 3 activates a splenic anti-inflammatory pathway: Evidence that cholinergic signals are transmitted via mesothelial cells

Ray, S. C., Baban, B., Tucker, M. A., Seaton, A. J., Chang, K. C., Mannon, E. C., Sun, J., Patel, B., Wilson, K., Musall, J. B., Ocasio, H., Irsik, D., Filosa, J. A., Sullivan, J. C., Marshall, B., Harris, R. A. & O'Connor, P. M., May 15 2018, In : Journal of Immunology. 200, 10, p. 3568-3586 19 p.

Research output: Contribution to journalArticle

Cholinergic Agents
Anti-Inflammatory Agents
Spleen
Esterases
Acetylcholine