Pediatric Hematology/Oncology

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Indoleamine-Pyrrole 2,3,-Dioxygenase Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Globins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Fetal Hemoglobin Medicine & Life Sciences
T-cells Chemical Compounds
Regulatory T-Lymphocytes Medicine & Life Sciences

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Projects 1988 2019

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells

Research Output 1987 2019

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Schaechter, K. M., Feser, C. J., Koehn, B. H., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

Retinal Dehydrogenase
Aldehyde Dehydrogenase
Graft vs Host Disease
Dendritic Cells

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Cao, Y., Trillo-Tinoco, J., Sierra, R. A., Anadon, C., Dai, W., Mohamed, E., Cen, L., Costich, T. L., Magliocco, A., Marchion, D., Klar, R., Michel, S., Jaschinski, F., Reich, R. R., Mehrotra, S., Cubillos-Ruiz, J. R., Munn, D. H., Conejo-Garcia, J. R. & Rodriguez, P. C., Dec 1 2019, In : Nature Communications. 10, 1, 1280.

Research output: Contribution to journalArticle

Open Access
Transcription Factor CHOP
endoplasmic reticulum
Endoplasmic Reticulum Stress

Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease

Zhu, X., Oseghale, A. R., Nicole, L. H., Li, B. & Pace, B. S., Feb 1 2019, In : Experimental Biology and Medicine. 244, 2, p. 171-182 12 p.

Research output: Contribution to journalReview article

Fetal Hemoglobin
Oxidative stress
Sickle Cell Anemia
Oxidative Stress
Sickle Hemoglobin