Pediatric Hematology/Oncology

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2020

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Yu, M., Guo, G., Huang, L., Deng, L., Chang, C. S., Achyut, B. R., Canning, M., Xu, N., Arbab, A. S., Bollag, R. J., Rodriguez, P. C., Mellor, A. L., Shi, H., Munn, D. H. & Cui, Y., Dec 1 2020, In : Nature communications. 11, 1, 515.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2 Scopus citations

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Thangavelu, G., Du, J., Paz, K. G., Loschi, M., Zaiken, M. C., Flynn, R., Taylor, P. A., Kirchmeier, A. K., Panoskaltsis-Mortari, A., Luznik, L., MacDonald, K. P., Hill, G. R., Maillard, I., Munn, D. H., Serody, J. S., Murphy, W. J., Miklos, D., Cutler, C. S., Koreth, J., Antin, J. H. & 5 others, Soiffer, R. J., Ritz, J., Dahlberg, C., Miller, A. T. & Blazar, B. R., Jan 1 2020, In : Blood. 135, 1, p. 28-40 13 p.

Research output: Contribution to journalArticle

The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

Mohamed, E., Sierra, R. A., Trillo-Tinoco, J., Cao, Y., Innamarato, P., Payne, K. K., de Mingo Pulido, A., Mandula, J., Zhang, S., Thevenot, P., Biswas, S., Abdalla, S. K., Costich, T. L., Hänggi, K., Anadon, C. M., Flores, E. R., Haura, E. B., Mehrotra, S., Pilon-Thomas, S., Ruffell, B. & 4 others, Munn, D. H., Cubillos-Ruiz, J. R., Conejo-Garcia, J. R. & Rodriguez, P. C., Apr 14 2020, In : Immunity. 52, 4, p. 668-682.e7

Research output: Contribution to journalArticle

1 Scopus citations
2019

Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice

Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 2019, In : Blood Cells, Molecules, and Diseases. 79, 102345.

Research output: Contribution to journalArticle

1 Scopus citations

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, B. H., Saha, A., McDonald-Hyman, C., Loschi, M., Thangavelu, G., Ma, L., Zaiken, M., Dysthe, J., Krepps, W., Panthera, J., Hippen, K., Jameson, S. C., Miller, J. S., Cooper, M. A., Farady, C. J., Iwawaki, T., Ting, J. P. Y., Serody, J. S., Murphy, W. J., Hill, G. R. & 5 others, Murray, P. J., Bronte, V., Munn, D. H., Zeiser, R. & Blazar, B. R., Nov 7 2019, In : Blood. 134, 19, p. 1670-1682 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Melanie Schaechter, K., Feser, C. J., Koehn, B. H., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of Immunology. 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, A., Taylor, P. A., Lees, C. J., Panoskaltsis-Mortari, A., Osborn, M. J., Feser, C. J., Thangavelu, G., Melchinger, W., Refaeli, Y., Hill, G. R., Munn, D. H., Murphy, W. J., Serody, J. S., Maillard, I., Kreymborg, K., van den Brink, M., Dong, C., Huang, S., Zang, X., Allison, J. P. & 2 others, Zeiser, R. & Blazar, B. R., 2019, In : JCI Insight. 4, 19, e127716.

Research output: Contribution to journalArticle

Open Access

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Cao, Y., Trillo-Tinoco, J., Sierra, R. A., Anadon, C., Dai, W., Mohamed, E., Cen, L., Costich, T. L., Magliocco, A., Marchion, D., Klar, R., Michel, S., Jaschinski, F., Reich, R. R., Mehrotra, S., Cubillos-Ruiz, J. R., Munn, D. H., Conejo-Garcia, J. R. & Rodriguez, P. C., Dec 1 2019, In : Nature communications. 10, 1, 1280.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Feature article: δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis

Liu, L., Zhu, X., Yu, A., Ward, C. M. & Pace, B. S., Oct 1 2019, In : Experimental Biology and Medicine. 244, 14, p. 1220-1232 13 p.

Research output: Contribution to journalArticle

Open Access

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

Halaby, M. J., Hezaveh, K., Lamorte, S., Ciudad, M. T., Kloetgen, A., MacLeod, B. L., Guo, M., Chakravarthy, A., Medina, T. D. S., Ugel, S., Tsirigos, A., Bronte, V., Munn, D. H., Pugh, T. J., De Carvalho, D. D., Butler, M. O., Ohashi, P. S., Brooks, D. G. & McGaha, T. L., Dec 13 2019, In : Science immunology. 4, 42

Research output: Contribution to journalArticle

3 Scopus citations

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In : Experimental Hematology. 70, p. 85-96.e5

Research output: Contribution to journalArticle

10 Scopus citations

MIR29B mediates epigenetic mechanisms of HBG gene activation

Starlard-Davenport, A., Smith, A., Vu, L., Li, B. & Pace, B. S., Jul 2019, In : British Journal of Haematology. 186, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

Paz, K., Flynn, R., Du, J., Tannheimer, S., Johnson, A. J., Dong, S., Stark, A. K., Okkenhaug, K., Panoskaltsis-Mortari, A., Sage, P. T., Sharpe, A. H., Luznik, L., Ritz, J., Soiffer, R. J., Cutler, C. S., Koreth, J., Antin, J. H., Miklos, D. B., MacDonald, K. P., Hill, G. R. & 10 others, Maillard, I., Serody, J. S., Murphy, W. J., Munn, D. H., Feser, C., Zaiken, M., Vanhaesebroeck, B., Turka, L. A., Byrd, J. C. & Blazar, B. R., Jun 2019, In : American Journal of Transplantation. 19, 6, p. 1820-1830 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

33 Scopus citations

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Habtetsion, T., Ding, Z-C., Pi, W., Li, T., Lu, C., Chen, T., Xi, C., Spartz, H., Liu, K., Hao, Z., Mivechi, N. F., Huo, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Aug 7 2018, In : Cell Metabolism. 28, 2, p. 228-242.e6

Research output: Contribution to journalArticle

10 Scopus citations

Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans article

Shinde, R., Hezaveh, K., Halaby, M. J., Kloetgen, A., Chakravarthy, A., Da Silva Medina, T., Deol, R., Manion, K. P., Baglaenko, Y., Eldh, M., Lamorte, S., Wallace, D., Chodisetti, S. B., Ravishankar, B., Liu, H., Chaudhary, K., Munn, D. H., Tsirigos, A., Madaio, M., Gabrielsson, S. & 4 others, Touma, Z., Wither, J., De Carvalho, D. D. & McGaha, T. L., Jun 1 2018, In : Nature Immunology. 19, 6, p. 571-582 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model

Zhu, X., Xi, C., Thomas, B. & Pace, B. S., Feb 1 2018, In : Blood. 131, 5, p. 558-562 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors

Nayak-Kapoor, A., Hao, Z., Sadek, R., Dobbins, R., Marshall, L., Vahanian, N. N., Jay Ramsey, W., Kennedy, E., Mautino, M. R., Link, C. J., Lin, R. S., Royer-Joo, S., Liang, X., Salphati, L., Morrissey, K. M., Mahrus, S., McCall, B., Pirzkall, A., Munn, D. H., Janik, J. E. & 1 others, Khleif, S. N., Jun 20 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 61.

Research output: Contribution to journalArticle

27 Scopus citations

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

McDonald-Hyman, C., Muller, J. T., Loschi, M., Thangavelu, G., Saha, A., Kumari, S., Reichenbach, D. K., Smith, M. J., Zhang, G., Koehn, B. H., Lin, J., Mitchell, J. S., Fife, B. T., Panoskaltsis-Mortari, A., Feser, C. J., Kirchmeier, A. K., Osborn, M. J., Hippen, K. L., Kelekar, A., Serody, J. S. & 6 others, Turka, L. A., Munn, D. H., Chi, H., Neubert, T. A., Dustin, M. L. & Blazar, B. R., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4604-4621 18 p.

Research output: Contribution to journalArticle

7 Scopus citations
2017

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Ding, Z-C., Habtetsion, T., Cao, Y., Li, T., Liu, C., Kuczma, M., Chen, T., Hao, Z., Bryan, L. J., Munn, D. H. & Zhou, G., Dec 1 2017, In : Scientific reports. 7, 1, 12168.

Research output: Contribution to journalArticle

7 Scopus citations

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Mangaonkar, A., Mondal, A. K., Fulzule, S., Pundkar, C., Park, E. J., Jillella, A., Kota, V., Xu, H., Savage, N. M., Shi, H., Munn, D. & Kolhe, R., Dec 1 2017, In : Scientific reports. 7, 1, 12892.

Research output: Contribution to journalArticle

11 Scopus citations

Development and evaluation of two abbreviated questionnaires for mentoring and research self-efficacy

Jeffe, D. B., Rice, T. K., Boyington, J. E. A., Rao, D. C., Jean-Louis, G., Dávila-Román, V. G., Taylor, A. L., Pace, B. S. & Boutjdir, M., Mar 1 2017, In : Ethnicity and Disease. 27, 2, p. 179-188 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Early career mentoring through the American Society of Pediatric Hematology/Oncology: Lessons learned from a pilot program

Badawy, S. M., Black, V., Meier, E. R., Myers, K. C., Pinkney, K., Hastings, C., Hilden, J. M., Zweidler-McKay, P., Stork, L. C., Johnson, T. S. & Vaiselbuh, S. R., Mar 1 2017, In : Pediatric Blood and Cancer. 64, 3, e26252.

Research output: Contribution to journalArticle

8 Scopus citations

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

Hippen, K. L., O'Connor, R. S., Lemire, A. M., Saha, A., Hanse, E. A., Tennis, N. C., Merkel, S. C., Kelekar, A., Riley, J. L., Levine, B. L., June, C. H., Turka, L. A., Kean, L. S., MacMillan, M. L., Miller, J. S., Wagner, J. E., Munn, D. H. & Blazar, B. R., Dec 2017, In : American Journal of Transplantation. 17, 12, p. 3098-3113 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mentored training to increase diversity among faculty in the biomedical sciences: The NHL BI Summer Institute Programs to Increase Diversity (SI PID ) and the Programs to Increase Diversity among Individuals Engaged in Health-related Research (PRIDE )

Rice, T. K., Jeffe, D. B., Boyington, J. E. A., Jobe, J. B., Dávila-Román, V. G., Gonzalez, J. E., De Las Fuentes, L., Makala, L. H. C., Sarkar, R., Ogedegbe, G. G., Taylor, A. L., Czajkowski, S., Rao, D. C., Pace, B. S., Jean-Louis, G. & Boutjdir, M., Jun 1 2017, In : Ethnicity and Disease. 27, 3, p. 249-256 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002

Ring, E. K., Li, R., Moore, B. P., Nan, L., Kelly, V. M., Han, X., Beierle, E. A., Markert, J. M., Leavenworth, J. W., Gillespie, G. Y. & Friedman, G. K., Dec 15 2017, In : Molecular Therapy - Oncolytics. 7, p. 27-36 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Promoter methylation modulates indoleamine 2,3-dioxygenase 1 induction by activated T cells in human breast cancers

Noonepalle, S. K., Gu, F., Lee, E. J., Choi, J. H., Han, Q., Kim, J., Ouzounova, M., Shull, A. Y., Pei, L., Hsu, P. Y., Kolhe, R., Shi, F., Choi, J., Chiou, K., Huang, T. H. M., Korkaya, H., Deng, L., Xin, H. B., Huang, S., Thangaraju, M. & 5 others, Sreekumar, A., Ambs, S., Tang, S. C., Munn, D. H. & Shi, H., Apr 2017, In : Cancer Immunology Research. 5, 4, p. 330-344 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Stroke in a child with hemoglobin SC disease: A case report describing use of hydroxyurea after transfusion therapy

Fridlyand, D., Wilder, C., Clay, E. L. J., Gilbert, B. & Pace, B. S., Jan 1 2017, In : Pediatric Reports. 9, 1, 6984.

Research output: Contribution to journalArticle

1 Scopus citations

TFE3-positive renal cell carcinoma occurring in three children with dysfunctional kidneys on immunosuppression

Schaefer, B. A., Johnson, T. S., Hooper, D. K., Nathan, J. D. & Geller, J. I., Jun 2017, In : Pediatric Transplantation. 21, 4, e12912.

Research output: Contribution to journalArticle

2016

Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains

Hossain, M. A., Shen, Y., Knudson, I., Thakur, S., Stees, J. R., Qiu, Y., Pace, B. S., Peterson, K. R. & Bungert, J., Jan 1 2016, In : Molecular Therapy - Nucleic Acids. 5, p. e378

Research output: Contribution to journalArticle

6 Scopus citations

Biomechanical and biochemical regulation of cathepsin K expression in endothelial cells converge at AP-1 and NF-κB

Keegan, P. M., Anbazhakan, S., Kang, B., Pace, B. S. & Platt, M. O., May 1 2016, In : Biological Chemistry. 397, 5, p. 459-468 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., Chinnadurai, R., Manicassamy, B., He, Y., Mellor, A. L., Thangaraju, M., Munn, D. H. & Manicassamy, S., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalArticle

25 Scopus citations

IL-7 signaling imparts polyfunctionality and stemness potential to CD4+ T cells

Ding, Z-C., Liu, C., Cao, Y., Habtetsion, T., Kuczma, M., Pi, W., Kong, H., Cacan, E., Greer, S. F., Cui, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Jun 2 2016, In : OncoImmunology. 5, 6, e1171445.

Research output: Contribution to journalArticle

8 Scopus citations

Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicine

Goodman, S. R., Pace, B. S., Hansen, K. C., D’alessandro, A., Xia, Y., Daescu, O. & Glatt, S. J., Jan 1 2016, In : Experimental Biology and Medicine. 241, 7, p. 772-781 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

MiR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

Lu, Y., Hippen, K. L., Lemire, A. L., Gu, J., Wang, W., Ni, X., Ranganathan, P., Levine, B. L., Riley, J. L., June, C. H., Turka, L. A., Munn, D. H., Garzon, R., Lu, L. & Blazar, B. R., Sep 8 2016, In : Blood. 128, 10, p. 1424-1435 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells

Ward, C. M., Li, B. & Pace, B. S., Jan 1 2016, In : Experimental Biology and Medicine. 241, 7, p. 719-729 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease

Liu, L., Pertsemlidis, A., Ding, L. H., Story, M. D., Steinberg, M. H., Sebastiani, P., Hoppe, C., Ballas, S. K. & Pace, B. S., Jan 1 2016, In : Experimental Biology and Medicine. 241, 7, p. 706-718 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Saha, A., O'Connor, R. S., Thangavelu, G., Lovitch, S. B., Dandamudi, D. B., Wilson, C. B., Vincent, B. G., Tkachev, V., Pawlicki, J. M., Furlan, S. N., Kean, L. S., Aoyama, K., Taylor, P. A., Panoskaltsis-Mortari, A., Foncea, R., Ranganathan, P., Devine, S. M., Burrill, J. S., Guo, L., Sacristan, C. & 15 others, Snyder, N. W., Blair, I. A., Milone, M. C., Dustin, M. L., Riley, J. L., Bernlohr, D. A., Murphy, W. J., Fife, B. T., Munn, D. H., Miller, J. S., Serody, J. S., Freeman, G. J., Sharpe, A. H., Turka, L. A. & Blazar, B. R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2642-2660 19 p.

Research output: Contribution to journalArticle

43 Scopus citations

Sickle cell disease severity: an introduction

Pace, B. S. & Goodman, S. R., Jan 1 2016, In : Experimental Biology and Medicine. 241, 7, p. 677-678 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

Lemos, H., Mohamed, E., Huang, L., Ou, R., Pacholczyk, G., Arbab, A. S., Munn, D. & Mellor, A. L., Apr 15 2016, In : Cancer Research. 76, 8, p. 2076-2081 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Flynn, R., Paz, K., Du, J., Reichenbach, D. K., Taylor, P. A., Panoskaltsis-Mortari, A., Vulic, A., Luznik, L., MacDonald, K. K. P., Hill, G. R., Nyuydzefe, M. S., Weiss, J. M., Chen, W., Trzeciak, A., Serody, J. S., Aguilar, E. G., Murphy, W. J., Maillard, I., Munn, D. H., Koreth, J. & 6 others, Cutler, C. S., Antin, J. H., Ritz, J., Waksal, S. D., Zanin-Zhorov, A. & Blazar, B. R., Apr 28 2016, In : Blood. 127, 17, p. 2144-2154 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

McDonald-Hyman, C., Flynn, R., Panoskaltsis-Mortari, A., Peterson, N., MacDonald, K. P. A., Hill, G. R., Luznik, L., Serody, J. S., Murphy, W. J., Maillard, I., Munn, D. H., Turka, L. A., Koreth, J., Cutler, C. S., Soiffer, R. J., Antin, J. H., Ritz, J. & Blazar, B. R., Aug 18 2016, In : Blood. 128, 7, p. 1013-1017 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Huang, L., Ou, R., Rabelo de Souza, G., Cunha, T. M., Lemos, H., Mohamed, E., Li, L., Pacholczyk, G., Randall, J., Munn, D. H. & Mellor, A. L., May 2016, In : PLoS Pathogens. 12, 5, e1005615.

Research output: Contribution to journalArticle

17 Scopus citations
2015

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Veenstra, R. G., Flynn, R., Kreymborg, K., McDonald-Hyman, C., Saha, A., Taylor, P. A., Osborn, M. J., Panoskaltsis-Mortari, A., Schmitt-Graeff, A., Lieberknecht, E., Murphy, W. J., Serody, J. S., Munn, D. H., Freeman, G. J., Allison, J. P., Mak, T. W., Van Brink, M. D., Zeiser, R. & Blazar, B. R., Jan 1 2015, In : Blood. 125, 21, p. 3335-3346 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., Manicassamy, B., Koni, P. A., Thangaraju, M., Sun, Z., Mellor, A. L., Munn, D. H. & Manicassamy, S., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3295-3304 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

Pace, B. S., Liu, L., Li, B. & Makala, L. H., Jan 1 2015, In : Experimental Biology and Medicine. 240, 8, p. 1050-1064 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Changes in the amino acid sequence of the recombinant human factor VIIa analog, vatreptacog alfa, are associated with clinical immunogenicity

Mahlangu, J. N., Weldingh, K. N., Lentz, S. R., Kaicker, S., Karim, F. A., Matsushita, T., Recht, M., Tomczak, W., Windyga, J., Ehrenforth, S., Knobe, K., Weltermann, A., de Paula, E., Cerqueira, M., Zupancic-Salek, S., Katsarou, O., Economou, M., Nemes, L., Boda, Z., Santagostino, E. & 22 others, Tagariello, G., Hanabusa, H., Fukutake, K., Shima, M., Serban, M., Elezo-vic, I., Savic, A., Shen, M., Chuansumrit, A., Angchaisuksiri, P., Kavakli, K., Sasmaz, I., Madan, B., Giangrande, P., Kempton, C., Young, G., Quon, D., Ameri, A., Kuriakose, P., Obzut, D., Wang, M. & Ortiz, I., Nov 2015, In : Journal of Thrombosis and Haemostasis. 13, 11, p. 1989-1998 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
29 Scopus citations

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Koehn, B. H., Apostolova, P., Haverkamp, J. M., Miller, J. S., McCullar, V., Tolar, J., Munn, D. H., Murphy, W. J., Brickey, W. J., Serody, J. S., Gabrilovich, D. I., Bronte, V., Murray, P. J., Ting, J. P. Y., Zeiser, R. & Blazar, B. R., Sep 24 2015, In : Blood. 126, 13, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

48 Scopus citations