• 19809 Citations
  • 67 h-Index
1992 …2020

Research output per year

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Research Output

Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death: Involvement of serine but not cysteine proteases

Dong, Z., Saikumar, P., Weinberg, J. M. & Venkatachalam, M. A., Nov 1997, In : American Journal of Pathology. 151, 5, p. 1205-1213 9 p.

Research output: Contribution to journalArticle

208 Scopus citations

Intracellular Ca2+ thresholds that determine survival or death of energy-deprived cells

Dong, Z., Saikumar, P., Griess, G. A., Weinberg, J. M. & Venkatachalam, M. A., Jan 1998, In : American Journal of Pathology. 152, 1, p. 231-240 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Introduction: Autophagy in kidneys

Dong, Z., Jan 1 2014, In : Seminars in Nephrology. 34, 1, 1 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Invariant NKT cell development and function in microRNA-223 knockout mice

Li, K., Seo, K. H., Gao, T., Zheng, Q., Qi, R. Q., Wang, H., Weiland, M., Dong, Z., Mi, Q. S. & Zhou, L., May 1 2011, In : International Immunopharmacology. 11, 5, p. 561-568 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Irisin is induced in renal ischemia-reperfusion to protect against tubular cell injury via suppressing p53

Liu, Y., Fu, Y., Liu, Z., Shu, S., Wang, Y., Cai, J., Tang, C. & Dong, Z., Jul 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 7, 165792.

Research output: Contribution to journalArticle

KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism

Zhao, E., Ding, J., Xia, Y., Liu, M., Ye, B., Choi, J. H., Yan, C., Dong, Z., Huang, S., Zha, Y., Yang, L., Cui, H. & Ding, H. F., Jan 26 2016, In : Cell Reports. 14, 3, p. 506-519 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Lack of TNF-α promotes caspase-3-independent apoptosis during murine cytomegalovirus retinitis

Zhang, M., Covar, J., Marshall, B., Dong, Z. & Atherton, S. S., Mar 2011, In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1800-1808 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lipopolysaccharide Induces Chronic Kidney Injury and Fibrosis through Activation of mTOR Signaling in Macrophages

Chen, H., Zhu, J., Liu, Y., Dong, Z., Liu, H., Liu, Y., Zhou, X., Liu, F. & Chen, G., Nov 27 2015, In : American Journal of Nephrology. 42, 4, p. 305-317 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Lithium in kidney diseases: Big roles for the smallest metal

Livingston, M. J. & Dong, Z., Mar 2014, In : Journal of the American Society of Nephrology. 25, 3, p. 421-423 3 p.

Research output: Contribution to journalEditorial

3 Scopus citations

Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury

Rao, X., Zhong, J., Zhang, S., Zhang, Y., Yu, Q., Yang, P., Wang, M-H., Fulton, D. J., Shi, H., Dong, Z., Wang, D. & Wang, C. Y., Jun 28 2011, In : Circulation. 123, 25, p. 2964-2974 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Loss of microRNAs in thymus perturbs invariant NKT cell development and function

Seo, K. H., Zhou, L., Meng, D., Xu, J., Dong, Z. & Mi, Q. S., Nov 2010, In : Cellular and Molecular Immunology. 7, 6, p. 447-453 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mangiferin attenuate sepsis-induced acute kidney injury via antioxidant and anti-inammatory effects

He, L., Peng, X., Zhu, J., Chen, X., Liu, H., Tang, C., Dong, Z., Liu, F. & Peng, Y., May 22 2014, In : American Journal of Nephrology. 40, 5, p. 441-450 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

MBD2 upregulates MIR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

Wang, J., Li, H., Qiu, S., Dong, Z., Xiang, X. & Zhang, D., Oct 12 2017, In : Cell Death and Disease. 8, 10, e3120.

Research output: Contribution to journalArticle

18 Scopus citations

Mechanisms of cell death in hypoxia/reoxygenation injury

Saikumar, P., Dong, Z., Weinberg, J. M. & Venkatachalam, M. A., Jan 1 1998, In : Oncogene. 17, 25, p. 3341-3349 9 p.

Research output: Contribution to journalArticle

223 Scopus citations

MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression

Zha, Y., Xia, Y., Ding, J., Choi, J. H., Yang, L., Dong, Z., Yan, C., Huang, S. & Ding, H. F., Jan 1 2014, In : Cell Death and Disease. 5, 9, e1417.

Research output: Contribution to journalArticle

23 Scopus citations

Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway

Xia, Y., Ye, B., Ding, J., Yu, Y., Alptekin, A., Thangaraju, M., Prasad, P. D., Ding, Z. C., Park, E. J., Choi, J. H., Gao, B., Fiehn, O., Yan, C., Dong, Z., Zha, Y. & Ding, H. F., Aug 1 2019, In : Cancer Research. 79, 15, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival

Bhatt, K., Zhou, L., Mi, Q. S., Huang, S., She, J-X. & Dong, Z., Sep 2010, In : Molecular Medicine. 16, 9-10, p. 409-416 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

MicroRNA-375 is induced in cisplatin nephrotoxicity to repress hepatocyte nuclear factor 1-β

Hao, J., Lou, Q., Wei, Q., Mei, S., Li, L., Wu, G., Mi, Q. S., Mei, C. & Dong, Z., Mar 17 2017, In : Journal of Biological Chemistry. 292, 11, p. 4571-4582 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

MicroRNA-489 induction by hypoxia-inducible factor-1 protects against ischemic kidney injury

Wei, Q., Liu, Y., Liu, P., Hao, J., Liang, M., Mi, Q. S., Chen, J. K. & Dong, Z., 2016, In : Journal of the American Society of Nephrology. 27, 9, p. 2784-2796 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury

Wei, Q., Sun, H., Song, S., Liu, Y., Liu, P., Livingston, M. J., Wang, J., Liang, M., Mi, Q. S., Huo, Y., Nahman, N. S., Mei, C. & Dong, Z., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5448-5464 17 p.

Research output: Contribution to journalArticle

25 Scopus citations

MicroRNA-687 induced by hypoxia-inducible factor-1 targets phosphatase and tensin homolog in renal ischemia-reperfusion injury

Bhatt, K., Wei, Q., Pabla, N., Dong, G., Mi, Q. S., Liang, M., Mei, C. & Dong, Z., Jul 1 2015, In : Journal of the American Society of Nephrology. 26, 7, p. 1588-1596 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

MicroRNA deficiency in pancreatic islet cells exacerbates streptozotocin-induced murine autoimmune diabetes

Mi, Q. S., He, H. Z., Dong, Z., Isales, C. M. & Zhou, L., Aug 1 2010, In : Cell Cycle. 9, 15, p. 3199-3201 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

MicroRNA expression profiling identifies potential serum biomarkers for non-segmental vitiligo

Shi, Y. L., Weiland, M., Li, J., Hamzavi, I., Henderson, M., Huggins, R. H., Mahmoud, B. H., Agbai, O., Mi, X., Dong, Z., Lim, H. W., Mi, Q. S. & Zhou, L., May 1 2013, In : Pigment Cell and Melanoma Research. 26, 3, p. 418-421 4 p.

Research output: Contribution to journalLetter

20 Scopus citations

MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function

Zhou, L., Park, J. J., Zheng, Q., Dong, Z. & Mi, Q., Sep 2011, In : Cellular and Molecular Immunology. 8, 5, p. 380-387 8 p.

Research output: Contribution to journalReview article

26 Scopus citations

Micro RNAs are required for Langerhans cell, skin- and lung-resident macrophage ontogeny

Yao, Y., Martin, C., Yin, C., Guo, C., Dong, Z., Zhou, L. & Mi, Q. S., Sep 2018, In : Journal of Allergy and Clinical Immunology. 142, 3, p. 976-978.e2

Research output: Contribution to journalArticle

3 Scopus citations

MicroRNAs in kidneys: Biogenesis, regulation, and pathophysiological roles

Bhatt, K., Mi, Q. S. & Dong, Z., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F602-F610

Research output: Contribution to journalReview article

122 Scopus citations

MicroRNAs in Pathogenesis of Acute Kidney Injury

Liu, Z., Wang, S., Mi, Q. S. & Dong, Z., Nov 1 2016, In : Nephron. 134, 3, p. 149-153 5 p.

Research output: Contribution to journalReview article

15 Scopus citations

Microsomal prostaglandin synthase-1-derived prostaglandin E2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress

Jia, Z., Guo, X., Zhang, H., Wang, M-H., Dong, Z. & Yang, T., Nov 2008, In : Hypertension. 52, 5, p. 952-959 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Minocycline Up-regulates Bcl-2 and Protects against Cell Death in Mitochondria

Wang, J., Wei, Q., Wang, C. Y., Hill, W. D., Hess, D. C. & Dong, Z., May 7 2004, In : Journal of Biological Chemistry. 279, 19, p. 19948-19954 7 p.

Research output: Contribution to journalArticle

220 Scopus citations

MiR-214 represses mitofusin-2 to promote renal tubular apoptosis in ischemic acute kidney injury

Yan, Y., Ma, Z., Zhu, J., Zeng, M., Liu, H. & Dong, Z., Apr 2020, In : American Journal of Physiology - Renal Physiology. 318, 4, p. F878-F887

Research output: Contribution to journalArticle

2 Scopus citations

miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice

Wu, D., Bi, X., Qu, L., Han, L., Yin, C., Deng, J., Dong, Z., Mi, Q. S. & Zhou, L., Jan 1 2017, In : Experimental Dermatology. 26, 1, p. 82-84 3 p.

Research output: Contribution to journalLetter

3 Scopus citations

Mitochondria in kidney injury: When the power plant fails

Tang, C. & Dong, Z., 2016, In : Journal of the American Society of Nephrology. 27, 7, p. 1869-1872 4 p.

Research output: Contribution to journalEditorial

18 Scopus citations

Mitochondrial dynamics: Regulatory mechanisms and emerging role in renal pathophysiology

Zhan, M., Brooks, C., Liu, F., Sun, L. & Dong, Z., Apr 2013, In : Kidney International. 83, 4, p. 568-581 14 p.

Research output: Contribution to journalReview article

165 Scopus citations

Mitochondrial dysfunction in obesity-related kidney disease: a novel therapeutic target

Tang, C., Cai, J. & Dong, Z., Nov 1 2016, In : Kidney International. 90, 5, p. 930-933 4 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

Mitochondrial dysregulation and protection in cisplatin nephrotoxicity

Yang, Y., Liu, H., Liu, F. & Dong, Z., Jun 2014, In : Archives of Toxicology. 88, 6, p. 1249-1256 8 p.

Research output: Contribution to journalReview article

77 Scopus citations

Mitochondrial Function and Disturbances in the Septic Kidney

Parikh, S. M., Yang, Y., He, L., Tang, C., Zhan, M. & Dong, Z., Jan 1 2015, In : Seminars in Nephrology. 35, 1, p. 108-119 12 p.

Research output: Contribution to journalReview article

69 Scopus citations

Mitochondrial morphological dynamics in apoptosis

Brooks, C., Dong, Z. & Lever, S., Jan 1 2010, Apoptosis: Modern Insights into Disease from Molecules to Man. CRC Press, p. 131-146 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular cloning and characterization of the mouse Acdp gene family

Wang, C. Y., Yang, P., Shi, J. D., Purohit, S., Guo, D., An, H., Gu, J. G., Ling, J., Dong, Z. & She, J. X., Jan 15 2004, In : BMC Genomics. 5, 7.

Research output: Contribution to journalArticle

37 Scopus citations

Mouse model of ischemic acute kidney injury: Technical notes and tricks

Wei, Q. & Dong, Z., Dec 1 2012, In : American Journal of Physiology - Renal Physiology. 303, 11, p. F1487-F1494

Research output: Contribution to journalReview article

138 Scopus citations

mPGES-1 deletion impairs diuretic response to acute water loading

Soodvilai, S., Jia, Z., Wang, M. H., Dong, Z. & Yang, T., May 2009, In : American Journal of Physiology - Renal Physiology. 296, 5, p. F1129-F1135

Research output: Contribution to journalArticle

31 Scopus citations

mPGES-1 deletion potentiates urine concentrating capability after water deprivation

Jia, Z., Liu, G., Downton, M., Dong, Z., Zhang, A. & Yang, T., Apr 15 2012, In : American Journal of Physiology - Renal Physiology. 302, 8, p. F1005-F1012

Research output: Contribution to journalArticle

20 Scopus citations

mTOR contributes to ER stress and associated apoptosis in renal tubular cells

Dong, G., Liu, Y., Zhang, L., Huang, S., Ding, H. F. & Dong, Z., 2015, In : American Journal of Physiology - Renal Physiology. 308, 3, p. F267-F274

Research output: Contribution to journalArticle

23 Scopus citations

MTOR signaling regulates protective activity of transferred CD4-/-Foxp3-/- T cells in repair of acute kidney injury

Chen, G., Dong, Z., Liu, H., Liu, Y., Duan, S., Liu, Y., Liu, F. & Chen, H., Nov 15 2016, In : Journal of Immunology. 197, 10, p. 3917-3926 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Multiple-microarray analysis for identification of hub genes involved in tubulointerstial injury in diabetic nephropathy

Zeng, M., Liu, J., Yang, W., Zhang, S., Liu, F., Dong, Z., Peng, Y., Sun, L. & Xiao, L., Sep 1 2019, In : Journal of Cellular Physiology. 234, 9, p. 16447-16462 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

Patil, M., Pabla, N., Ding, H. F. & Dong, Z., Aug 15 2013, In : Cell Cycle. 12, 16, p. 2608-2616 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Nek1 phosphorylates von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

Patil, M., Pabla, N., Huang, S. & Dong, Z., Jan 1 2013, In : Cell Cycle. 12, 1, p. 166-171 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Netrin-1 regulates the inflammatory response of neutrophils and macrophages, and suppresses ischemic acute kidney injury by inhibiting COX-2-mediated PGE2 production

Ranganathan, P. V., Jayakumar, C., Mohamed, R., Dong, Z. & Ramesh, G., Jun 2013, In : Kidney International. 83, 6, p. 1087-1098 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Neutrophil extracellular traps in ischemic AKI: new way to kill

Liu, J. & Dong, Z., Feb 2018, In : Kidney International. 93, 2, p. 303-305 3 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation

Zheng, M., Cai, J., Liu, Z., Shu, S., Wang, Y., Tang, C. & Dong, Z., Jun 2019, In : Journal of Cellular and Molecular Medicine. 23, 6, p. 3995-4004 10 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury

Liu, H., Jia, Z., Soodvilai, S., Guan, G., Wang, M. H., Dong, Z., Symons, J. D. & Yang, T., Oct 2008, In : American Journal of Physiology - Renal Physiology. 295, 4, p. F942-F949

Research output: Contribution to journalArticle

55 Scopus citations