Biochemistry and Molecular Biology

Research Output

Article

cDNA cloning and functional analysis of the p97 subunit of the 265 proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11

Tsurumi, C., Shimizu, Y., Saeki, M., Kato, S., Demartino, G. N., Slaughter, C. A., Fujimuro, M., Yokosawa, H., Yamasaki, M. O., Hendil, K. B., Toh-E, A., Tanahashi, N. & Tanaka, K., 1996, In : European Journal of Biochemistry. 239, 3, p. 912-921 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

CDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family

Fujiwara, T., Watanabe, T. K., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Jun 3 1996, In : FEBS Letters. 387, 2-3, p. 184-188 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA

Russell, D. W., Yamamoto, T., Schneider, W. J., Slaughter, C. A., Brown, M. S. & Goldstein, J. L., 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 24 I, p. 7501-7505 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

Wu, X., Prasad, P. D., Leibach, F. H. & Ganapathy, V., May 29 1998, In : Biochemical and Biophysical Research Communications. 246, 3, p. 589-595 7 p.

Research output: Contribution to journalArticle

298 Scopus citations

Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of α(v) integrins

Huang, S., Stupack, D., Liu, A., Cheresh, D. & Nemerow, G. R., Apr 6 2000, In : Oncogene. 19, 15, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes

Bhagirath, D., Zhao, X., West, W. W., Qiu, F., Band, H. & Band, V., 2015, In : Oncotarget. 6, 11, p. 9018-9030 13 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cell type-specific release of matrix-metallo-proteinase-9 by bacterial chemoattractant in human blood phagocytic leukocytes

Doerner, A. M., Chen, L. Y., Ye, R. D., Yong, J., Huang, S. & Pan, Z. K., Feb 22 2011, In : International Journal of Clinical and Experimental Medicine. 4, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

Wu, C. H., Van Riggelen, J., Yetil, A., Fan, A. C., Bachireddy, P. & Felsher, D. W., Aug 7 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 32, p. 13028-13033 6 p.

Research output: Contribution to journalArticle

269 Scopus citations

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

Lingle, W. L., Lutz, W. H., Ingle, J. N., Maihle, N. J. & Salisbury, J. L., Mar 17 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 6, p. 2950-2955 6 p.

Research output: Contribution to journalArticle

405 Scopus citations

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloidderived suppressor cells

Liu, F., Li, X., Lu, C., Bai, A., Bielawski, J., Bielawska, A., Marshall, B., Schoenlein, P. V., Lebedyeva, I. O. & Liu, K., 2016, In : Oncotarget. 7, 51, p. 83907-83925 19 p.

Research output: Contribution to journalArticle

34 Scopus citations

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes

Coe, G. L., Redd, P. S., Paschall, A. V., Lu, C., Gu, L., Cai, H., Albers, T., Lebedyeva, I. O. & Liu, K., Aug 4 2016, In : Scientific reports. 6, 30816.

Research output: Contribution to journalArticle

11 Scopus citations

Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression

Paschall, A. V., Zimmerman, M. A., Torres, C. M., Yang, D., Chen, M. R., Li, X., Bieberich, E., Bai, A., Bielawski, J., Bielawska, A. & Liu, K., Jan 15 2014, In : BMC Cancer. 14, 1, 24.

Research output: Contribution to journalArticle

38 Scopus citations

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Wang, R., Islam, B. N., Bridges, A., Sharman, S. K., Hu, M., Hou, Y., Somanath, P. R., Venable, L., Singh, N., Kim, S., Sridhar, S., Hofmann, F. & Browning, D. D., Feb 1 2017, In : American Journal of Pathology. 187, 2, p. 377-389 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer

Xue, N., Lai, F., Du, T., Ji, M., Liu, D., Yan, C., Zhang, S., Yu, X., Jin, J. & Chen, X., Sep 1 2019, In : Cellular and Molecular Life Sciences. 76, 17, p. 3433-3447 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Characteristics of the genome of Arsenophonus nasoniae, son-killer bacterium of the wasp Nasonia

Darby, A. C., Choi, J. H., Wilkes, T., Hughes, M. A., Werren, J. H., Hurst, G. D. D. & Colbourne, J. K., Feb 2010, In : Insect Molecular Biology. 19, SUPPL. 1, p. 75-89 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Characterization of [Re2Cl3(μ-dppm)2(NCCH3) 2][Cl] and [Re2Cl3(μ-dppm)2(NCC6H 5)2][Cl] · 2CH2Cl2 by X-ray Crystallographic and Two-Dimensional NMR Spectroscopic Techniques

Concolino, T. E., Eglin, J. L., Hadden, C. E., Hicks, R. P., Staples, R. J., Valente, E. J. & Zubkowski, J. D., Jan 1 2000, In : Journal of Cluster Science. 11, 1, p. 109-123 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of a human globin enhancer element.

Tuan, D. Y., Solomon, W. B., Cavallesco, R., Huang, G. & London, I. M., 1989, In : Progress in clinical and biological research. 316 A, p. 63-72 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells

Prasad, P. D., Ramamoorthy, S., Leibach, F. H. & Ganapathy, V., 1997, In : Placenta. 18, 7, p. 527-533 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Characterization of N 5-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells

Huang, W., Prasad, P. D., Kekuda, R., Leibach, F. H. & Ganapathy, V., 1997, In : Investigative Ophthalmology and Visual Science. 38, 8, p. 1578-1587 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Characterization of pressure-mediated vascular tone in resistance arteries from bile duct-ligated rats

Jadeja, R. N., Thounaojam, M. C. & Khurana, S., 2017, In : Oncotarget. 8, 19, p. 30706-30722 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Characterization of progesterone receptor binding to the 90- and 70- kDa heat shock proteins

Schowalter, D. B., Sullivan, W. P., Maihle, N. J., Dobson, A. D. W., Conneely, O. M., O'Malley, B. W. & Toft, D. O., 1991, In : Journal of Biological Chemistry. 266, 31, p. 21165-21173 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

Characterization of the main phase transition in 1,2-dipalmitoyl-phosphatidylcholine LUVs by 1H NMR

Kennedy, A., Hmel, P. J., Seelbaugh, J., Quiles, J. G., Hicks, R. & Reid, T. J., Dec 12 2002, In : Journal of Liposome Research. 12, 3, p. 221-237 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Chemoattractant-stimulated NF-κB Activation Is Dependent on the Low Molecular Weight GTPase RhoA

Huang, S., Chen, L. Y., Zuraw, B. L., Ye, R. D. & Pan, Z. K., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 40977-40981 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Chemokine and chemokine receptor expression in kidney tumors: Molecular profiling of histological subtypes and association with metastasis

Gahan, J. C., Gosalbez, M., Yates, T., Young, E. E., Escudero, D. O., Chi, A., Garcia-Roig, M., Satyanarayana, R., Soloway, M. S., Bird, V. G. & Lokeshwar, V. B., Mar 2012, In : Journal of Urology. 187, 3, p. 827-833 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype

Ding, Z. C., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Mar 25 2010, In : Blood. 115, 12, p. 2397-2406 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Knight, R. A., Scicli, A. G. & Arbab, A. S., 2016, In : Cancer Biology and Therapy. 17, 3, p. 280-90 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer

Bhutia, Y. D., Ogura, J., Grippo, P. J., Torres, C., Sato, T., Wachtel, M., Ramachandran, S., Babu, E., Sivaprakasam, S., Rajasekaran, D., Schniers, B., On, N., Smoot, L., Thangaraju, M., Gnana-Prakasam, J. P. & Ganapathy, V., Mar 2020, In : Asian Journal of Pharmaceutical Sciences. 15, 2, p. 237-251 15 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Chronic granulomatous disease 100% corrected by displacement bone marrow transplantation from a volunteer unrelated donor

Hobbs, J. R., Monteil, M., McCluskey, D. R., Jurges, E. & El Tumi, M., Nov 1992, In : European Journal of Pediatrics. 151, 11, p. 806-810 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Circadian clocks regulate adenylyl cyclase activity rhythms in human RPE cells

Pavan, B., Frigato, E., Pozzati, S., Prasad, P. D., Bertolucci, C. & Biondi, C., Nov 10 2006, In : Biochemical and Biophysical Research Communications. 350, 1, p. 169-173 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Circulating miR-583 and miR-663 Refer to ZHENG differentiation in chronic hepatitis B

Zhang, H., Guan, Y., Lu, Y. Y., Hu, Y. Y., Huang, S. & Su, S. B., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 751341.

Research output: Contribution to journalArticle

7 Scopus citations

Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway

Jiang, M., Wang, C. Y., Huang, S., Yang, T. & Dong, Z., May 2009, In : American Journal of Physiology - Renal Physiology. 296, 5, p. F983-F993

Research output: Contribution to journalArticle

75 Scopus citations

Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress

Lee, H., Chung, H., Arnouk, H., Powell, F. L., Hunt, R. C., Hrushesky, W. J. M., Wood, P. A., Lee, S. H. & Jahng, W. J., Aug 2010, In : International Journal of Biological Macromolecules. 47, 2, p. 104-108 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Climatic variables are associated with seasonal acute asthma admissions to accident and emergency room facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T. & Monteil, M. A., Nov 1 2003, In : Clinical and Experimental Allergy. 33, 11, p. 1526-1530 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Clinical efficacy of modified preoperative neoadjuvant chemotherapy in the treatment of locally advanced (stage IB2 to IIB) ervical ancer: randomized study

Chen, H., Liang, C., Zhang, L., Huang, S. & Wu, X., Sep 1 2008, In : Gynecologic Oncology. 110, 3, p. 308-315 8 p.

Research output: Contribution to journalArticle

99 Scopus citations

Clinical Parameters Outperform Molecular Subtypes for Predicting Outcome in Bladder Cancer: Results from Multiple Cohorts, Including TCGA

Morera, D. S., Hasanali, S. L., Belew, D., Ghosh, S., Klaassen, Z., Jordan, A. R., Wang, J., Terris, M. K., Bollag, R. J., Merseburger, A. S., Stenzl, A., Soloway, M. S. & Lokeshwar, V. B., Jan 1 2020, In : The Journal of urology. 203, 1, p. 62-72 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cloning and characterization of a potential-sensitive organic cation transporter (OCT3) from rat placenta

Kekuda, R., Prasad, P. D., Wu, X., Leibach, F. H. & Ganapathy, V., Mar 20 1998, In : FASEB Journal. 12, 5, p. A1043

Research output: Contribution to journalArticle

1 Scopus citations

Cloning and expression of a b0,+-like amino acid transporter functioning asa heterodimer with 4F2hc-instead of rBAT. A new candidate gene for cystinuria

Rajan, D. P., Kekuda, R., Huang, W., Wang, H., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29005-29010 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Cloning and functional characterization of a Na+-independent, broad-specific neutral amino acid transporter from mammalian intestine

Rajan, D. P., Kekuda, R., Huang, W., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 15 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1463, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Cloning and functional characterization of a new subtype of the amino acid transport system N

Nakanishi, T., Kekuda, R., Fei, Y. J., Hatanaka, T., Sugawara, M., Martindale, R. G., Leibach, F. H., Prasad, P. D. & Ganapathy, V., 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1757-C1768

Research output: Contribution to journalArticle

86 Scopus citations

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

Kekuda, R., Prasad, P. D., Wu, X., Wang, H., Fei, Y. J., Leibach, F. H. & Ganapathy, V., Jun 26 1998, In : Journal of Biological Chemistry. 273, 26, p. 15971-15979 9 p.

Research output: Contribution to journalArticle

361 Scopus citations

Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney

Gopal, E., Umapathy, N. S., Martin, P. M., Ananth, S., Gnana-Prakasam, J. P., Becker, H., Wagner, C. A., Ganapathy, V. & Prasad, P. D., Nov 2007, In : Biochimica et Biophysica Acta - Biomembranes. 1768, 11, p. 2690-2697 8 p.

Research output: Contribution to journalArticle

56 Scopus citations
47 Scopus citations

Cloning and functional expression of a cDNA encoding a mammalian sodium- dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate

Prasad, P. D., Wang, H., Kekuda, R., Fujita, T., Fei, Y. J., Devoe, L. D., Leibach, F. H. & Ganapathy, V., Mar 27 1998, In : Journal of Biological Chemistry. 273, 13, p. 7501-7508 8 p.

Research output: Contribution to journalArticle

164 Scopus citations

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

Wang, H., Huang, W., Sugawara, M., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jul 14 2000, In : Biochemical and Biophysical Research Communications. 273, 3, p. 1175-1179 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)

Kekuda, R., Prasad, P. D., Fei, Y. J., Leibach, F. H. & Ganapathy, V., Dec 13 1996, In : Biochemical and Biophysical Research Communications. 229, 2, p. 553-558 6 p.

Research output: Contribution to journalArticle

358 Scopus citations

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

Srinivas, S. R., Gopal, E., Zhuang, L., Itagaki, S., Martin, P. M., Fei, Y. J., Ganapathy, V. & Prasad, P. D., Dec 15 2005, In : Biochemical Journal. 392, 3, p. 655-664 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Cloning of a functional sodium-dependent pantothenate/biotin transporter from rabbit intestine and Caco-2 cells

Prasad, P. D., Sheikh, S., Huang, W., Leibach, F. H. & Ganapathy, V., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

2 Scopus citations

Cloning of murine tissue factor and regulation of gene expression by transforming growth factor type β1

Ranganathan, G., Blatti, S. P., Subramaniam, M., Fass, D. N., Maihle, N. J. & Getz, M. J., 1991, In : Journal of Biological Chemistry. 266, 1, p. 496-501 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cloning of the human thiamine transporter, a member of the folate transporter family

Dutta, B., Huang, W., Molero, M., Kekuda, R., Leibach, F. H., Devoe, L. D., Ganapathy, V. & Prasad, P. D., Nov 5 1999, In : Journal of Biological Chemistry. 274, 45, p. 31925-31929 5 p.

Research output: Contribution to journalArticle

143 Scopus citations

Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter B(o) from a human placental choriocarcinoma cell line

Kekuda, R., Prasad, P. D., Fei, Y. J., Torres-Zamorano, V., Sinha, S., Yang-Feng, T. L., Leibach, F. H. & Ganapathy, V., Oct 7 1996, In : Journal of Biological Chemistry. 271, 31, p. 18657-18661 5 p.

Research output: Contribution to journalArticle

211 Scopus citations