Biochemistry and Molecular Biology

Research Output

2016

YM155 inhibits topoisomerase function

Hong, M., Ren, M. Q., Silva, J., Paul, A., Wilson, W. D., Schroeder, C., Weinberger, P., Janik, J. & Hao, Z., Oct 13 2016, In : Anti-Cancer Drugs. 28, 2, p. 142-152 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2015

53BP1 promotes microhomology-mediated end-joining in G1-phase cells

Xiong, X., Du, Z., Wang, Y., Feng, Z., Fan, P., Yan, C., Willers, H. & Zhang, J., Jan 1 2015, In : Nucleic Acids Research. 43, 3, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
3 Scopus citations

A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis

Hou, Y., Wu, Y., Farooq, S. M., Guan, X., Wang, S., Liu, Y., Oblak, J. J., Holcomb, J., Jiang, Y., Strieter, R. M., Lasley, R. D., Arbab, A. S., Sun, F., Li, C. & Yang, Z., Mar 1 2015, In : Stem Cell Research. 14, 2, p. 133-143 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

A federated network for translational cancer research using clinical data and biospecimens

Jacobson, R. S., Becich, M. J., Bollag, R. J., Chavan, G., Corrigan, J., Dhir, R., Feldman, M. D., Gaudioso, C., Legowski, E., Maihle, N. J., Mitchell, K., Murphy, M., Sakthivel, M., Tseytlin, E. & Weaver, J., Dec 15 2015, In : Cancer Research. 75, 24, p. 5194-5201 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells

Lu, X., Ding, Z. C., Cao, Y., Liu, C., Habtetsion, T., Yu, M., Lemos, H., Salman, H., Xu, H., Mellor, A. L. & Zhou, G., Feb 15 2015, In : Journal of Immunology. 194, 4, p. 2011-2021 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy

Chaudhary, K., Shinde, R., Liu, H., Gnana-Prakasam, J. P., Veeranan-Karmegam, R., Huang, L., Ravishankar, B., Bradley, J., Kvirkvelia, N., McMenamin, M., Xiao, W., Kleven, D., Mellor, A. L., Madaio, M. P. & McGaha, T. L., Jun 15 2015, In : Journal of Immunology. 194, 12, p. 5713-5724 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

Powell, F. L., Mazzone, V., Persichini, T., Maraschi, A., Harris, B. M., Venema, R. C., Colasanti, M., Gliozzi, M., Muscoli, C., Bartoli, M. & Mollace, V., May 3 2015, In : Journal of Neuroinflammation. 12, 1, 84.

Research output: Contribution to journalArticle

23 Scopus citations

Article watch: September 2015

Slaughter, C. A., Sep 1 2015, In : Journal of Biomolecular Techniques. 26, 3, p. 113-117 5 p.

Research output: Contribution to journalArticle

Article watch: December 2015

Slaughter, C. A., Dec 1 2015, In : Journal of Biomolecular Techniques. 26, 4, p. 150-156 7 p.

Research output: Contribution to journalArticle

Assessing heavy metal and PCB exposure from tap water by measuring levels in plasma from sporadic breast cancer patients, a pilot study

Zimeri, A. M., Robb, S. W., Hassan, S. M., Hire, R. R. & Davis, M. B., Dec 9 2015, In : International journal of environmental research and public health. 12, 12, p. 15683-15691 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Assessing myogenic response and vasoactivity in resistance mesenteric arteries using pressure myography

Jadeja, R. N., Rachakonda, V., Bagi, Z. & Khurana, S., Jul 6 2015, In : Journal of Visualized Experiments. 2015, 101, p. 1-7 7 p., e50997.

Research output: Contribution to journalArticle

7 Scopus citations

A survey of computational methods in transcriptome-wide alternative splicing analysis

Wang, J., Ye, Z., Huang, T. H. M., Shi, H. & Jin, V., Mar 1 2015, In : Biomolecular Concepts. 6, 1, p. 59-66 8 p.

Research output: Contribution to journalReview article

6 Scopus citations

B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens

Shinde, R., Shimoda, M., Chaudhary, K., Liu, H., Mohamed, E., Bradley, J., Kandala, S., Li, X., Liu, K. & McGaha, T. L., Sep 1 2015, In : Journal of Immunology. 195, 5, p. 2374-2382 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks

Achyut, B. R., Shankar, A., Iskander, A. S. M., Ara, R., Angara, K., Zeng, P., Knight, R. A., Scicli, A. G. & Arbab, A. S., Dec 28 2015, In : Cancer Letters. 369, 2, p. 416-26 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Can Brown Fat Win the Battle Against White Fat?

Elattar, S. & Satyanarayana, A., Oct 1 2015, In : Journal of Cellular Physiology. 230, 10, p. 2311-2317 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., Manicassamy, B., Koni, P. A., Thangaraju, M., Sun, Z., Mellor, A. L., Munn, D. H. & Manicassamy, S., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3295-3304 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe

Bhuiyan, M. P. I., Aryal, M. P., Janic, B., Karki, K., Varma, N. R. S., Ewing, J. R., Arbab, A. S. & Ali, M. M., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 481-486 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Curcumin improves the tumoricidal effect of mitomycin C by suppressing ABCG2 expression in stem cell-like breast cancer cells

Zhou, Q., Ye, M., Lu, Y., Zhang, H., Chen, Q., Huang, S. & Su, S., Aug 25 2015, In : PloS one. 10, 8, e0136694.

Research output: Contribution to journalArticle

29 Scopus citations

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

Yang, L., Fang, D., Chen, H., Lu, Y., Dong, Z., Ding, H. F., Jing, Q., Su, S. B. & Huang, S., Jan 1 2015, In : Oncotarget. 6, 25, p. 20801-20812 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Deletion of the amino acid transporter SLC6A14 suppresses tumour growth in spontaneous mouse models of breast cancer

Babu, E., Bhutia, Y. D., Ramachandran, S., Gnana-Prakasam, J. P., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Jul 1 2015, In : Biochemical Journal. 469, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele

Davis, M. B., Walens, A., Hire, R., Mumin, K., Brown, A. M., Ford, D. J., Howerth, E. W. & Monteil, M., Oct 16 2015, In : PloS one. 10, 10, 140098.

Research output: Contribution to journalArticle

8 Scopus citations

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Pathania, R., Ramachandran, S., Elangovan, S., Padia, R., Yang, P., Cinghu, S., Veeranan-Karmegam, R., Arjunan, P., Gnana-Prakasam, J. P., Sadanand, F., Pei, L., Chang, C. S., Choi, J. H., Shi, H., Manicassamy, S., Prasad, P. D., Sharma, S., Ganapathy, V., Jothi, R. & Thangaraju, M., Apr 22 2015, In : Nature communications. 6, 6910.

Research output: Contribution to journalArticle

107 Scopus citations

E3 ubiquitin ligase Skp2 as an attractive target in cancer therapy

Hao, Z. & Huang, S., Jan 15 2015, In : Frontiers in Bioscience - Landmark. 20, 3, p. 474-490 17 p.

Research output: Contribution to journalReview article

34 Scopus citations

Effect of curcumin on pro-angiogenic factors in the xenograft model of breast cancer

Ferreira, L. C., Arbab, A. S., Jardim-Perassi, B. V., Borin, T. F., Varma, N. R. S., Iskander, A. S. M., Shankar, A., Ali, M. M. & de Campos Zuccari, D. A. P., Dec 1 2015, In : Anti-Cancer Agents in Medicinal Chemistry. 15, 10, p. 1285-1296 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Electrochemical Detection of Alginate Penetration in Immobilized Layer-by-Layer Films by Unnatural Amino Acid Containing Antimicrobial Peptides

Vinogradov, S. M., Satterwhite-Warden, J. E., Hicks, R. P., Anderson, E. & Hvastkovs, E. G., Dec 20 2015, In : Electrochimica Acta. 186, p. 245-252 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Epigenetic and Immune Regulation of Colorectal Cancer Stem Cells

Paschall, A. V. & Liu, K., Dec 1 2015, In : Current Colorectal Cancer Reports. 11, 6, p. 414-421 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Epigenetic regulation of apoptosis and cell cycle regulatory genes in human colon carcinoma cells

Paschall, A. V. & Liu, K., Sep 1 2015, In : Genomics Data. 5, p. 189-191 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Evolutionary divergence of core and post-translational circadian clock genes in the pitcher-plant mosquito, Wyeomyia smithii

Tormey, D., Colbourne, J. K., Mockaitis, K., Choi, J. H., Lopez, J., Burkhart, J., Bradshaw, W. & Holzapfel, C., Oct 6 2015, In : BMC Genomics. 16, 1, 754.

Research output: Contribution to journalArticle

9 Scopus citations

Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium

Wang, Y., Zhang, L., Li, Y., Chen, L., Wang, X., Guo, W., Zhang, X., Qin, G., He, S. H., Zimmerman, A., Liu, Y., Kim, I., Weintraub, N. L. & Tang, Y. L., Jun 9 2015, In : International Journal of Cardiology. 192, p. 61-69 9 p.

Research output: Contribution to journalArticle

152 Scopus citations

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass

Wang, G., Rajpurohit, S. K., Delaspre, F., Walker, S. L., White, D. T., Ceasrine, A., Kuruvilla, R., Li, R-J., Shim, J. S., Liu, J. O., Parsons, M. J. & Mumm, J. S., 2015, In : eLife. 4

Research output: Contribution to journalArticle

45 Scopus citations

Fluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging

Verma, V. K., Kamaraju, S. R., Kancherla, R., Kona, L. K., Beev, S. S., Debnath, T., Usha, S. P., Vadapalli, R., Arbab, A. S. & Chelluri, L. K., Jan 20 2015, In : International Journal of Nanomedicine. 10, p. 711-726 16 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fruit and vegetable intake and urinary levels of prostaglandin E2 metabolite in postmenopausal women

Kim, S., Rimando, J. & Sandler, D. P., May 19 2015, In : Nutrition and Cancer. 67, 4, p. 580-586 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells

Fukuhara, S., Chang, I., Mitsui, Y., Chiyomaru, T., Yamamura, S., Majid, S., Saini, S., Deng, G., Gill, A., Wong, D. K., Shiina, H., Nonomura, N., Lau, Y. F. C., Dahiya, R. & Tanaka, Y., Jan 1 2015, In : Oncotarget. 6, 18, p. 16341-16351 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Glycyrrhetinic acid potently suppresses breast cancer invasion and metastasis by impairing the p38 MAPK-AP1 signaling axis

Wang, X. F., Zhou, Q. M., Lu, Y. Y., Zhang, H., Huang, S. & Su, S. B., May 1 2015, In : Expert Opinion on Therapeutic Targets. 19, 5, p. 577-587 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

H3K9 trimethylation silences fas expression to confer colon carcinoma immune escape and 5-fluorouracil chemoresistance

Paschall, A. V., Yang, D., Lu, C., Choi, J-H., Li, X., Liu, F., Figueroa, M., Oberlies, N. H., Pearce, C., Bollag, W. B., Nayak, A. & Liu, K., Aug 15 2015, In : Journal of Immunology. 195, 4, p. 1868-1882 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Hepatoprotective Potential of Herbal Medicine

Jadeja, R., Devkar, R. V. & Nammi, S., Jan 1 2015, In : Evidence-based Complementary and Alternative Medicine. 2015, 536564.

Research output: Contribution to journalEditorial

Open Access

Identification of gene signatures regulated by carvedilol in mouse heart

Teoh, J. P., Park, K. M., Broskova, Z., Jimenez, F. R., Bayoumi, A. S., Archer, K., Su, H., Johnson, J., Weintraub, N. L., Tang, Y. & Kim, I. M., Sep 1 2015, In : Physiological Genomics. 47, 9, p. 376-385 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells

Lee, E. J., Rath, P., Liu, J., Ryu, D., Pei, L., Noonepalle, S. K., Shull, A. Y., Feng, Q., Litofsky, N. S., Miller, D. C., Anthony, D. C., Kirk, M. D., Laterra, J., Deng, L., Xin, H. B., Wang, X., Choi, J. H. & Shi, H., Jul 20 2015, In : Journal of Genetics and Genomics. 42, 7, p. 355-371 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

Identification of the mitochondrial heme metabolism complex

Medlock, A. E., Shiferaw, M. T., Marcero, J. R., Vashisht, A. A., Wohlschlegel, J. A., Phillips, J. D. & Dailey, H. A., Aug 19 2015, In : PloS one. 10, 8, e0135896.

Research output: Contribution to journalArticle

31 Scopus citations

IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation

Paschall, A. V., Zhang, R., Qi, C. F., Bardhan, K., Peng, L., Lu, G., Yang, J., Merad, M., McGaha, T., Zhou, G., Mellor, A., Abrams, S. I., Morse, H. C., Ozato, K., Xiong, H. & Liu, K., Mar 1 2015, In : Journal of Immunology. 194, 5, p. 2369-2379 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

IFNγ induces DNA methylation-silenced GPR109A expression via pSTAT1/p300 and H3K18 acetylation in colon cancer

Bardhan, K., Paschall, A. V., Yang, D., Chen, M. R., Simon, P. S., Bhutia, Y. D., Martin, P. M., Thangaraju, M., Browning, D. D., Ganapathy, V., Heaton, C. M., Gu, K., Lee, J. R. & Liu, K., Jul 1 2015, In : Cancer Immunology Research. 3, 7, p. 795-805 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Increased oxidative and nitrative stress accelerates aging of the retinal vasculature in the diabetic retina

Lamoke, F., Shaw, S., Yuan, J., Ananth, S., Duncan, M., Martin, P. & Bartoli, M., Oct 14 2015, In : PloS one. 10, 10, e0139664.

Research output: Contribution to journalArticle

30 Scopus citations

Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds

Lang, L., Ding, H., Chen, X., Sun, S. Y., Liu, G. & Yan, C., Jul 24 2015, In : Chemistry and Biology. 22, 7, p. 957-964 8 p., 3080.

Research output: Contribution to journalArticle

3 Scopus citations

ITagPlot: An accurate computation and interactive drawing tool for tag density plot

Kim, S. H., Ezenwoye, O., Cho, H. G., Robertson, K. D. & Choi, J-H., Jan 1 2015, In : Bioinformatics. 31, 14, p. 2384-2387 4 p.

Research output: Contribution to journalArticle

Lifetime use of nonsteroidal anti-inflammatory drugs and breast cancer risk: Results from a prospective study of women with a sister with breast cancer

Kim, S., Shore, D. L., Wilson, L. E., Sanniez, E. I., Kim, J. H., Taylor, J. A. & Sandler, D. P., Dec 16 2015, In : BMC Cancer. 15, 1, 960.

Research output: Contribution to journalArticle

18 Scopus citations

Long non-coding RNAs as master regulators in cardiovascular diseases

Archer, K., Broskova, Z., Bayoumi, A. S., Teoh, J. P., Davila, A., Tang, Y., Su, H. & Kim, I. M., Oct 5 2015, In : International journal of molecular sciences. 16, 10, p. 23651-23667 17 p.

Research output: Contribution to journalReview article

72 Scopus citations

Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model

Wang, Z., Xu, D., Ding, H., Kim, J., Zhang, J., Hai, T. & Yan, C., Sep 17 2015, In : Oncogene. 34, 38, p. 4975-4984 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice

Rachakonda, V., Jadeja, R. N., Urrunaga, N. H., Shah, N., Ahmad, D., Cheng, K., Twaddell, W. S., Raufman, J. P. & Khurana, S., Sep 16 2015, In : Scientific reports. 5, 14110.

Research output: Contribution to journalArticle

5 Scopus citations