Biochemistry and Molecular Biology

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1999

Molecular and ligand-binding characterization of the σ-receptor in the Jurkat human T lymphocyte cell line

Ganapathy, M. E., Prasad, P. D., Huang, W., Seth, P., Leibach, F. H. & Ganapathy, V., Apr 1999, In : Journal of Pharmacology and Experimental Therapeutics. 289, 1, p. 251-260 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

NF-κB activation is required for C5a-induced interleukin-8 gene expression in mononuclear cells

Hsu, M. H., Wang, M., Browning, D. D., Mukaida, N. & Ye, R. D., May 15 1999, In : Blood. 93, 10, p. 3241-3249 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits

Ping, P., Zhang, J., Huang, S., Cao, X., Tang, X. L., Li, R. C. X., Zheng, Y. T., Qiu, Y., Clerk, A., Sugden, P., Han, J. & Bolli, R., Nov 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 277, 5 46-5, p. H1771-H1785

Research output: Contribution to journalArticle

116 Scopus citations

Primary structure and functional characteristics of a mammalian sodium- coupled high affinity dicarboxylate transporter

Kekuda, R., Wang, H., Huang, W., Pajor, A. M., Leibach, F. H., Devoe, L. D., Prasad, P. D. & Ganapathy, V., Feb 5 1999, In : Journal of Biological Chemistry. 274, 6, p. 3422-3429 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Serum sErbB1 and epidermal growth factor levels as tumor biomarkers in women with stage III or IV epithelial ovarian cancer

Baron, A. T., Lafky, J. M., Boardman, C. H., Balasubramaniam, S., Suman, V. J., Podratz, K. C. & Maihle, N. J., Feb 1 1999, In : Cancer Epidemiology Biomarkers and Prevention. 8, 2, p. 129-137 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Sickle cell telemedicine and standard clinical encounters: A comparison of patient satisfaction

Woods, K. F., Kutlar, A., Johnson, J. A., Waller, J. L., Grigsby, R. K., Stachura, M. E. & Rahn, D. W., Dec 1 1999, In : Telemedicine Journal. 5, 4, p. 349-356 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Tyrosine phosphorylation of caldesmon is required for binding to the Shc·Grb2 complex

Wang, Z., Danielsen, A. J., Maihle, N. J. & McManus, M. J., Nov 19 1999, In : Journal of Biological Chemistry. 274, 47, p. 33807-33813 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2000

A (GATA)7 motif located in the 5' boundary area of the human β-globin locus control region exhibits silencer activity in erythroid cells

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan, D., 2000, In : American Journal of Hematology. 65, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

Xie, P., Browning, D. D., Hay, N., Mackman, N. & Ye, R. D., Aug 11 2000, In : Journal of Biological Chemistry. 275, 32, p. 24907-24914 8 p.

Research output: Contribution to journalArticle

118 Scopus citations

Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of Epstein-Barr virus-transformed B cells

Von Seggern, D. J., Huang, S., Fleck, S. K., Stevenson, S. C. & Nemerow, G. R., 2000, In : Journal of Virology. 74, 1, p. 354-362 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

A retrospective analysis of invasive Streptococcus pneumoniae infections in Trinidad.

Williams, K. P. & Monteil, M. A., Mar 2000, In : The West Indian medical journal. 49, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Autocrine regulation of interleukin-8 production in human monocytes

Browning, D. D., Diehl, W. C., Hsu, M. H., Schraufstatter, I. U. & Ye, R. D., 2000, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 279, 6 23-6, p. L1129-L1136

Research output: Contribution to journalArticle

45 Scopus citations

BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines

Thangaraju, M., Kaufmann, S. H. & Couch, F. J., Oct 27 2000, In : Journal of Biological Chemistry. 275, 43, p. 33487-33496 10 p.

Research output: Contribution to journalArticle

113 Scopus citations

Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis

Liu, D., Martino, G., Thangaraju, M., Sharma, M., Halwani, F., Shen, S. H., Patel, Y. C. & Srikant, C. B., Mar 31 2000, In : Journal of Biological Chemistry. 275, 13, p. 9244-9250 7 p.

Research output: Contribution to journalArticle

102 Scopus citations

cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome

McCutchen-Maloney, S. L., Matsuda, K., Shimbara, N., Binns, D. D., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Jun 16 2000, In : Journal of Biological Chemistry. 275, 24, p. 18557-18565 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of α(v) integrins

Huang, S., Stupack, D., Liu, A., Cheresh, D. & Nemerow, G. R., Apr 6 2000, In : Oncogene. 19, 15, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization of [Re2Cl3(μ-dppm)2(NCCH3) 2][Cl] and [Re2Cl3(μ-dppm)2(NCC6H 5)2][Cl] · 2CH2Cl2 by X-ray Crystallographic and Two-Dimensional NMR Spectroscopic Techniques

Concolino, T. E., Eglin, J. L., Hadden, C. E., Hicks, R. P., Staples, R. J., Valente, E. J. & Zubkowski, J. D., Jan 1 2000, In : Journal of Cluster Science. 11, 1, p. 109-123 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cloning and functional characterization of a Na+-independent, broad-specific neutral amino acid transporter from mammalian intestine

Rajan, D. P., Kekuda, R., Huang, W., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jan 15 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1463, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

Wang, H., Huang, W., Sugawara, M., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., Jul 14 2000, In : Biochemical and Biophysical Research Communications. 273, 3, p. 1175-1179 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Descriptive epidemiology of asthma in Trinidad, West Indies

Monteil, M. A., Juman, S., Hassanally, R., Williams, K. P., Pierre, L., Rahaman, M., Singh, H. & Trinidade, A., Jan 1 2000, In : Journal of Asthma. 37, 8, p. 677-684 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases

Ramchandran, R., Bengra, C., Whitney, B., Lanclos, K. & Tuan Lo, D., Sep 11 2000, In : American Journal of Hematology. 65, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Differential influence of the 4F2 heavy chain and the protein related to b0,+ amino acid transport on substrate affinity of the heteromeric b0,+ amino acid transporter

Rajan, D. P., Huang, W., Kekuda, R., George, R. L., Wang, J., Conway, S. J., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., May 12 2000, In : Journal of Biological Chemistry. 275, 19, p. 14331-14335 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Electrogenic nature of rat sodium-dependent multivitamin transport

Prasad, P. D., Srinivas, S. R., Wang, H., Leibach, F. H., Devoe, L. D. & Ganapathy, V., Apr 21 2000, In : Biochemical and Biophysical Research Communications. 270, 3, p. 836-840 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Evaluation of an isogenic major outer membrane protein-deficient mutant in the human model of Haemophilus ducreyi infection

Throm, R. E., Al-Tawfiq, J. A., Fortney, K. R., Katz, B. P., Hood, A. F., Slaughter, C. A., Hansen, E. J. & Spinola, S. M., May 2000, In : Infection and Immunity. 68, 5, p. 2602-2607 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Examination of the activity of carboxyl-terminal chimeric constructs of human and yeast ferrochelatases

Medlock, A. E. & Dailey, H. A., Jun 27 2000, In : Biochemistry. 39, 25, p. 7461-7467 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor α in mammalian retinal pigment epithelium

Chancy, C. D., Kekuda, R., Huang, W., Prasad, P. D., Kuhnel, J. M., Sirotnak, F. M., Roon, P., Ganapathy, V. & Smith, S. B., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20676-20684 9 p.

Research output: Contribution to journalArticle

118 Scopus citations

In organello formaldehyde crosslinking of proteins to mtDNA: Identification of bifunctional proteins

Kaufman, B. A., Newman, S. M., Hallberg, R. L., Slaughter, C. A., Perlman, P. S. & Butow, R. A., Jul 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 14, p. 7772-7777 6 p.

Research output: Contribution to journalArticle

159 Scopus citations

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

Arthur, W. T., Petch, L. A. & Burridge, K., Jun 1 2000, In : Current Biology. 10, 12, p. 719-722 4 p.

Research output: Contribution to journalArticle

362 Scopus citations

Nitric oxide activation of p38 mitogen-activated protein kinase in 293T fibroblasts requires cGMP-dependent protein kinase

Browning, D. D., McShane, M. P., Marty, C. & Ye, R. D., Jan 28 2000, In : Journal of Biological Chemistry. 275, 4, p. 2811-2816 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

PKCε modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes

Li, R. C. X., Ping, P., Zhang, J., Wead, W. B., Cao, X., Gao, J., Zheng, Y., Huang, S., Han, J. & Bolli, R., 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 279, 4 48-4, p. H1679-H1689

Research output: Contribution to journalArticle

110 Scopus citations

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

Hatanaka, T., Huang, W., Wang, H., Sugawara, M., Prasad, P. D., Leibach, F. H. & Ganapathy, V., Jul 31 2000, In : Biochimica et Biophysica Acta - Biomembranes. 1467, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

115 Scopus citations

Primary structure genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+ - and H+ -coupled glutamine transporter

Fei, Y. J., Sugawara, M., Nakanishi, T., Huang, W., Wang, H., Prasad, P. D., Leibach, F. H. & Ganapathy, V., Aug 4 2000, In : Journal of Biological Chemistry. 275, 31, p. 23707-23717 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Proteolytic cleavage of the Fe - S subunit hinge region of Rhodobacter capsulatus bc1 complex: Effects of inhibitors and mutations

Valkova-Valchanova, M., Darrouzet, E., Moomaw, C. R., Slaughter, C. A. & Daldal, F., Dec 19 2000, In : Biochemistry. 39, 50, p. 15484-15492 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Ras-independent oncogenic transformation by an EGF-receptor mutant

Boerner, J. L., McManus, M. J., Martin, G. S. & Maihle, N. J., Apr 12 2000, In : Journal of Cell Science. 113, 6, p. 935-942 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Solution structures in SDS micelles and functional activity at the bullfrog substance P receptor of ranatachykinin peptides

Perrine, S. A., Whitehead, T. L., Hicks, R. P., Szarek, J. L., Krause, J. E. & Simmons, M. A., May 30 2000, In : Journal of Medicinal Chemistry. 43, 9, p. 1741-1753 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Stable and unstable transgene integration sites in the human genome: extinction of the Green Fluorescent Protein transgene in K562 cells

Migliaccio, A. R., Bengra, C., Ling, J., Pi, W., Li, C., Zeng, S., Keskintepe, M., Whitney, B., Sanchez, M., Migliaccio, G. & Tuan, D., Oct 3 2000, In : Gene. 256, 1-2, p. 197-214 18 p.

Research output: Contribution to journalArticle

35 Scopus citations

Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms

Whitfield, M. L., Zheng, L. X., Baldwin, A., Ohta, T., Hurt, M. M. & Marzluff, W. F., Jun 2000, In : Molecular and Cellular Biology. 20, 12, p. 4188-4198 11 p.

Research output: Contribution to journalArticle

182 Scopus citations

Structure, function, and genomic organization of human Na+-dependent high-affinity dicarboxylate transporter

Wang, H., Fei, Y. J., Kekuda, R., Yang-Feng, T. L., Devoe, L. D., Leibach, F. H., Prasad, P. D. & Ganapathy, V., 2000, In : American Journal of Physiology - Cell Physiology. 278, 5 47-5, p. C1019-C1030

Research output: Contribution to journalArticle

66 Scopus citations

The alloreactive and self-restricted CD4+ T cell response directed against a single MHC class II/peptide combination

Kovalik, J. P., Singh, N., Mendiratta, S. K., Martin, W. D., Ignatowicz, L. & Van Kaer, L., Aug 1 2000, In : Journal of Immunology. 165, 3, p. 1285-1293 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The application of multidimensional NMR to the study of soil humic substances

Kingery, W. L., Simpson, A. J., Hayes, M. H. B., Locke, M. A. & Hicks, R. P., Jun 2000, In : Soil Science. 165, 6, p. 483-494 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The protein tyrosine phosphatase Shp-2 regulates RhoA activity

Schoenwaelder, S. M., Petch, L. A., Williamson, D., Shen, R., Feng, G. S. & Burridge, K., Nov 30 2000, In : Current Biology. 10, 23, p. 1523-1526 4 p.

Research output: Contribution to journalArticle

116 Scopus citations

Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38α mitogen-activated protein kinase activity

Huang, S., New, L., Pan, Z., Han, J. & Nemerow, G. R., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 12266-12272 7 p.

Research output: Contribution to journalArticle

121 Scopus citations
2001

A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37

Wu, E., Fernandez, J., Fleck, S. K., Von Seggern, D. J., Huang, S. & Nemerow, G. R., Jan 20 2001, In : Virology. 279, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4

Lee, H., Akita, R. W., Sliwkowski, M. X. & Maihle, N. J., Jun 1 2001, In : Cancer Research. 61, 11, p. 4467-4473 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

An incremental increase in the complexity of peptides bound to class II MHC changes the diversity of positively selected αβ TCRs

Pacholczyk, R., Kraj, P. & Ignatowicz, L., Feb 15 2001, In : Journal of Immunology. 166, 4, p. 2357-2363 7 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Moore, P., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental eye research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

122 Scopus citations

A preliminary study of serum concentrations of soluble epidermal growth factor receptor (sErbB1), gonadotropins, and steroid hormones in healthy men and women

Baron, A. T., Lafky, J. M., Maihle, N. J., Suman, V. J., Hillman, D. W., Buenafe, M. C., Boardman, C. H., Podratz, K. C. & Perez, E. A., 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 11, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Associations between climate variables and asthma visits to accident and emergency facilities in Trinidad, West Indies

Ivey, M. A., Simeon, D. T., Juman, S., Hassanally, R., Williams, K. & Monteil, M. A., Jan 1 2001, In : Allergology International. 50, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells

Liu, K., Li, Y., Prabhu, V., Young, L., Becker, K. G., Munson, P. J. & Weng, N. P., Jun 15 2001, In : Journal of Immunology. 166, 12, p. 7335-7344 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Chemoattractant-stimulated NF-κB Activation Is Dependent on the Low Molecular Weight GTPase RhoA

Huang, S., Chen, L. Y., Zuraw, B. L., Ye, R. D. & Pan, Z. K., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 40977-40981 5 p.

Research output: Contribution to journalArticle

39 Scopus citations