Biochemistry and Molecular Biology

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2006

Origin and T Cell Receptor Diversity of Foxp3+CD4+CD25+ T Cells

Pacholczyk, R., Ignatowicz, H., Kraj, P. & Ignatowicz, L., Aug 1 2006, In : Immunity. 25, 2, p. 249-259 11 p.

Research output: Contribution to journalArticle

229 Scopus citations

Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase

Taurin, S., Sandbo, N., Qin, Y., Browning, D. & Dulin, N. O., Apr 14 2006, In : Journal of Biological Chemistry. 281, 15, p. 9971-9976 6 p.

Research output: Contribution to journalArticle

290 Scopus citations

Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

Xu, Y., Huang, S., Liu, Z. G. & Han, J., Mar 31 2006, In : Journal of Biological Chemistry. 281, 13, p. 8788-8795 8 p.

Research output: Contribution to journalArticle

193 Scopus citations

Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus isolates from Trinidad & Tobago

Akpaka, P. E., Kissoon, S., Swanston, W. H. & Monteil, M., Jul 3 2006, In : Annals of Clinical Microbiology and Antimicrobials. 5, 16.

Research output: Contribution to journalArticle

22 Scopus citations

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases

Thangaraju, M., Gopal, E., Martin, P. M., Ananth, S., Smith, S. B., Prasad, P. D., Sterneck, E. & Ganapathy, V., Dec 15 2006, In : Cancer Research. 66, 24, p. 11560-11564 5 p.

Research output: Contribution to journalArticle

95 Scopus citations

Soluble epidermal growth factor receptor acridinium-linked immunosorbent assay.

Lafky, J. M., Baron, A. T. & Maihle, N. J., Jan 1 2006, In : Methods in molecular biology (Clifton, N.J.). 327, p. 39-47 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stromal-epithelial interaction in prostate cancer progression

Chung, L. W. K., Huang, W. C., Sung, S. Y., Wu, D., Odero-Marah, V., Nomura, T., Shigemura, K., Miyagi, T., Seo, S., Shi, C., Molitierno, J., Elmore, J., Anderson, C., Isotani, S., Edlund, M., Hsieh, C. L., Wang, R., Shehata, B. & Zhau, H. E., Jan 1 2006, In : Clinical Genitourinary Cancer. 5, 2, p. 162-170 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch

Giuriato, S., Ryeom, S., Fan, A. C., Bachireddy, P., Lynch, R. C., Rioth, M. J., Van Riggelen, J., Kopelman, A. M., Passegué, E., Tang, F., Folkman, J. & Felsher, D. W., Oct 31 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 44, p. 16266-16271 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration

Bian, D., Mahanivong, C., Yu, J., Frisch, S. M., Pan, Z. K., Ye, R. D. & Huang, S., Apr 6 2006, In : Oncogene. 25, 15, p. 2234-2244 11 p.

Research output: Contribution to journalArticle

86 Scopus citations

The Granulin-Epithelin Precursor Is a Steroid-Regulated Growth Factor in Endometrial Cancer

Jones, M. B., Houwink, A. P., Freeman, B. K., Greenwood, T. M., Lafky, J. M., Lingle, W. L., Berchuck, A., Maxwell, G. L., Podratz, K. C. & Maihle, N. J., May 1 2006, In : Journal of the Society for Gynecologic Investigation. 13, 4, p. 304-311 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis

Pondarré, C., Antiochos, B. B., Campagna, D. R., Clarke, S. L., Greer, E. L., Deck, K. M., McDonald, A., Han, A. P., Medlock, A., Kutok, J. L., Anderson, S. A., Eisenstein, R. S. & Fleming, M. D., Mar 1 2006, In : Human Molecular Genetics. 15, 6, p. 953-964 12 p.

Research output: Contribution to journalArticle

152 Scopus citations

The role of mast cells and eosinophils in chronic gastritis

Moorchung, N., Srivastava, A. N., Gupta, N. K., Malaviya, A. K., Achyut, B. R. & Mittal, B., Oct 2006, In : Clinical and Experimental Medicine. 6, 3, p. 107-14 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Up-regulation of the amino acid transporter ATB0,+ (SLC6A14) in carcinoma of the cervix

Gupta, N., Prasad, P. D., Ghamande, S., Moore-Martin, P., Herdman, A. V., Martindale, R. G., Podolsky, R., Mager, S., Ganapathy, M. E. & Ganapathy, V., Jan 1 2006, In : Gynecologic Oncology. 100, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

β2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis

Huang, W. C., Wu, D., Xie, Z., Zhau, H. E., Nomura, T., Zayzafoon, M., Pohl, J., Hsieh, C. L., Weitzmann, M. N., Farach-Carson, M. C. & Chung, L. W. K., Sep 15 2006, In : Cancer Research. 66, 18, p. 9108-9116 9 p.

Research output: Contribution to journalArticle

80 Scopus citations

β2-microglobulin promotes the growth of human renal cell carcinoma through the activation of the protein kinase A, cyclic AMP-responsive element-binding protein, and vascular endothelial growth factor axis

Nomura, T., Huang, W. C., Zhau, H. E., Wu, D., Xie, Z., Mimata, H., Zayzafoon, M., Young, A. N., Marshall, F. F., Weitzmann, M. N. & Chung, L. W. K., Dec 15 2006, In : Clinical Cancer Research. 12, 24, p. 7294-7305 12 p.

Research output: Contribution to journalArticle

56 Scopus citations
2005

African dust clouds are associated with increased paediatric asthma accident and emergency admissions on the Caribbean island of Trinidad

Gyan, K., Henry, W., Lacaille, S., Laloo, A., Lamsee-Ebanks, C., McKay, S., Antoine, R. M. & Monteil, M. A., Jul 1 2005, In : International Journal of Biometeorology. 49, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

A novel protein kinase C (PKCε) is required for fMet-Leu-Phe-induced activation of NF-κB in human peripheral blood monocytes

Chen, L. Y., Doerner, A., Lehmann, P. F., Huang, S., Zhong, G. & Pan, Z. K., Jun 10 2005, In : Journal of Biological Chemistry. 280, 23, p. 22497-22501 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs

Dalpiaz, A., Pavan, B., Vertuani, S., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Tanganelli, S., Ferraro, L., Marzola, G., Prasad, P. & Manfredini, S., Mar 2005, In : European Journal of Pharmaceutical Sciences. 24, 4, p. 259-269 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Biological functions of SLC5A8, a candidate tumour suppressor

Ganapathy, V., Gopal, E., Miyauchi, S. & Prasad, P. O., Feb 1 2005, In : Biochemical Society Transactions. 33, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

72 Scopus citations

C/EBPδ is a crucial regulator of pro-apoptotic gene expression during mammary gland involution

Thangaraju, M., Rudelius, M., Bierie, B., Raffeld, M., Sharan, S., Hennighausen, L., Huang, A. M. & Sterneck, E., Nov 1 2005, In : Development. 132, 21, p. 4675-4685 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)

Srinivas, S. R., Gopal, E., Zhuang, L., Itagaki, S., Martin, P. M., Fei, Y. J., Ganapathy, V. & Prasad, P. D., Dec 15 2005, In : Biochemical Journal. 392, 3, p. 655-664 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Comparison of prevalence and severity of asthma among adolescents in the Caribbean islands of Trinidad and Tobago: Results of a nationwide cross-sectional survey

Monteil, M. A., Joseph, G., Changkit, C., Wheeler, G. & Antoine, R. M., Sep 14 2005, In : BMC Public Health. 5, 96.

Research output: Contribution to journalArticle

17 Scopus citations

Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis

Liu, H. Y., Zheng, G., Treber, M., Dai, J. & Woldegiorgis, G., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4524-4531 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Epigenetic modulation of retinoic acid receptor β2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma

Wang, X. F., Qian, D. Z., Ren, M., Kato, Y., Wei, Y., Zhang, L., Fansler, Z., Clark, D., Nakanishi, O. & Pili, R., May 1 2005, In : Clinical Cancer Research. 11, 9, p. 3535-3542 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Genotypic analysis of the protease and reverse transcriptase of HIV type 1 subtype C isolates from antiretroviral drug-naive adults in Malawi

Petch, L. A., Hoffman, I. F., Jere, C. S., Kazembe, P. N., Martinson, F. E., Chilongozi, D., Fiscus, S. A. & Cohen, M. S., Sep 1 2005, In : AIDS Research and Human Retroviruses. 21, 9, p. 799-805 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Impaired retinoic acid (RA) signal leads to RARβ2 epigenetic silencing and RA resistance

Ren, M. Q., Pozzi, S., Bistulfi, G., Somenzi, G., Rossetti, S. & Sacchi, N., Dec 1 2005, In : Molecular and Cellular Biology. 25, 23, p. 10591-10603 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Inhibition of amino acid transport system A by interleukin-1β in trophoblasts

Thongsong, B., Subramanian, R. K., Ganapathy, V. & Prasad, P. D., Oct 1 2005, In : Journal of the Society for Gynecologic Investigation. 12, 7, p. 495-503 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

In vivo imaging of retinoic acid receptor β2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells

Qian, D. Z., Ren, M., Wei, Y., Wang, X., Van De Geijn, F., Rasmussen, C., Nakanishi, O., Sacchi, N. & Pili, R., Jun 15 2005, In : Prostate. 64, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Involvement of MicroRNA in AU-Rich Element-Mediated mRNA Instability

Jing, Q., Huang, S., Guth, S., Zarubin, T., Motoyama, A., Chen, J., Di Padova, F., Lin, S. C., Gram, H. & Han, J., Mar 11 2005, In : Cell. 120, 5, p. 623-634 12 p.

Research output: Contribution to journalArticle

652 Scopus citations

Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells

Van Riggelen, J., Buchwalter, G., Soto, U., De-Castro Arce, J., Zur Hausen, H., Wasylyk, B. & Rösl, F., Feb 4 2005, In : Journal of Biological Chemistry. 280, 5, p. 3286-3294 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Phenotypic analysis of EcR-A mutants suggests that EcR isoforms have unique functions during Drosophila development

Davis, M. B., Carney, G. E., Robertson, A. E. & Bender, M., Jun 15 2005, In : Developmental Biology. 282, 2, p. 385-396 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts

Bromann, P. A., Korkaya, H., Webb, C. P., Miller, J., Calvin, T. L. & Courtneidge, S. A., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10253-10263 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Selenocysteine tRNA identification in the model organisms Dictyostelium discoideum and Tetrahymena thermophila

Shrimali, R. K., Lobanov, A. V., Xu, X. M., Rao, M., Carlson, B. A., Mahadeo, D. C., Parent, C. A., Gladyshev, V. N. & Hatfield, D. L., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 147-151 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

Li, H., Ye, X., Mahanivong, C., Bian, D., Chun, J. & Huang, S., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10564-10571 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family

Gopal, E., Fei, Y. J., Miyauchi, S., Zhuang, L., Prasad, P. D. & Ganapathy, V., May 15 2005, In : Biochemical Journal. 388, 1, p. 309-316 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Soluble epidermal growth factor receptor (SEG-FR) and cancer antigen 125 (CA125) as screening and diagnostic tests for epithelial ovarian cancer

Baron, A. T., Boardman, C. H., Lafky, J. M., Rademaker, A., Liu, D., Fishman, D. A., Podratz, K. C. & Maihle, N. J., Feb 1 2005, In : Cancer Epidemiology Biomarkers and Prevention. 14, 2, p. 306-318 13 p.

Research output: Contribution to journalArticle

51 Scopus citations

Studies on epidermal growth factor receptor signaling in vertebrate limb patterning

Omi, M., Fisher, M., Maihle, N. J. & Dealy, C. N., Jun 1 2005, In : Developmental Dynamics. 233, 2, p. 288-300 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

The HS2 enhancer of the β-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter

Ling, J., Baibakov, B., Pi, W., Emerson, B. M. & Tuan, D., Jul 29 2005, In : Journal of Molecular Biology. 350, 5, p. 883-896 14 p.

Research output: Contribution to journalArticle

44 Scopus citations

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2

Yu, X., Zhu, X., Pi, W., Ling, J., Ko, L., Takeda, Y. & Tuan, D., Oct 21 2005, In : Journal of Biological Chemistry. 280, 42, p. 35184-35194 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Tolerization of dendritic cells by HLA-G

Ristich, V., Liang, S., Zhang, W., Wu, J. & Horuzsko, A., Apr 1 2005, In : European Journal of Immunology. 35, 4, p. 1133-1142 10 p.

Research output: Contribution to journalArticle

234 Scopus citations

Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans

Gupta, N., Miyauchi, S., Martindale, R. G., Herdman, A. V., Podolsky, R., Miyake, K., Mager, S., Prasad, P. D., Ganapathy, M. E. & Ganapathy, V., Jun 30 2005, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1741, 1-2, p. 215-223 9 p.

Research output: Contribution to journalArticle

65 Scopus citations
2004

Activation of the small GTPase Rac1 by cGMP-dependent protein kinase

Hou, Y., Ye, R. D. & Browning, D. D., Jan 1 2004, In : Cellular Signalling. 16, 9, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Amphiregulin Expression in Prostatic Intraepithelial Neoplasia and Adenocarcinoma: A Study of 93 Cases

Bostwick, D. G., Qian, J. & Maihle, N. J., Feb 1 2004, In : Prostate. 58, 2, p. 164-168 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

A retrospective study of the 1996 DEN-1 epidemic in Trinidad: Demographic and clinical features

Brown, T. U., Babb, K., Nimrod, M., Carrington, C. V. F., Salas, R. A. & Monteil, M. A., Dec 1 2004, In : Dengue Bulletin. 28, p. 7-19 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Creation of EcR isoform-specific mutations in Drosophila melanogaster via local P element transposition, imprecise P element excision, and male recombination

Carney, G. E., Robertson, A., Davis, M. B. & Bender, M., Apr 1 2004, In : Molecular Genetics and Genomics. 271, 3, p. 282-290 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Death of retinal neurons in streptozotocin-induced diabetic mice

Martin, P. M., Roon, P., Van Ells, T. K., Ganapathy, V. & Smith, S. B., Sep 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 9, p. 3330-3336 7 p.

Research output: Contribution to journalArticle

324 Scopus citations

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules

Manfredini, S., Vertuani, S., Pavan, B., Vitali, F., Scaglianti, M., Bortolotti, F., Biondi, C., Scatturin, A., Prasad, P. & Dalpiaz, A., Oct 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 20, p. 5453-5463 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Diet-induced obesity and mammary tumor development in MMTV-neu female mice

Cleary, M. P., Grande, J. P., Juneja, S. C. & Maihle, N. J., Dec 1 2004, In : Nutrition and Cancer. 50, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Dynamic retrotransposition of ERV-9 LTR and L1 in the β-globin gene locus during primate evolution

Ling, J., Zhang, L., Jin, H., Pi, W., Kosteas, T., Anagnou, N. P., Goodman, M. & Tuan, D., Mar 2004, In : Molecular Phylogenetics and Evolution. 30, 3, p. 867-871 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ectopic expression of nonliganded retinoic acid receptor β abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells

Arce, J. D. C., Soto, U., Van Riggelen, J., Schwarz, E., Zur Hausen, H. & Rösl, F., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45408-45416 9 p.

Research output: Contribution to journalArticle

10 Scopus citations